The use of NMR spectroscopy for the understanding of disease.
The use of NMR spectroscopy for the understanding of disease.
复制标题
使用核磁共振波谱来了解疾病。
作者：
G. Radda
核磁共振光谱法现在可以用来研究人体组织和器官的生物化学能量非侵入性。该方法已经增加了我们对一些肌肉疾病的理解，提供了有关全身功能，控制和激素状态的肌肉代谢信息，有助于阐明迄今尚未认识到的疾病原因，并产生了关于体内生物能量学控制的新想法。对人脑、肝脏、心脏和肾脏的生物化学研究才刚刚开始。对精心挑选的患者进行进一步的研究可能会使生物化学和临床实践更加紧密地联系在一起。
Nuclear magnetic resonance spectroscopy can now be used to investigate the biochemical energetics of human tissues and organs noninvasively. The method already has increased our understanding of some muscle diseases, has provided information from muscle metabolism about whole-body functions, control, and hormonal status, has helped in the elucidation of hitherto unrecognized causes of disease, and yielded new ideas about the control of bioenergetics in vivo. Studies on the biochemistry of human brain, liver, heart, and kidney are just beginning. Further investigations of well-selected patients are likely to bring biochemistry and clinical practice closer together.
使用底物类似物 β-胍基丙酸耗尽肌酸的心脏中的肌酸激酶动力学、ATP 周转率和心脏性能。
DOI：
10.1016/0167-4889(85)90148-x
发表时间：
1985
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Shoubridge,EA;Jeffry,FM;Keogh,JM;Radda,GK;Seymour,AM
通讯作者：
Seymour,AM
DOI：
10.1016/0006-291x(81)90915-3
发表时间：
1981-12
影响因子：
3.1
作者：
P. Matthews;J. Bland;D. Gadian;G. Radda
通讯作者：
P. Matthews;J. Bland;D. Gadian;G. Radda