Transamination by polymeric enzyme mimics
Transamination by polymeric enzyme mimics
复制标题
DOI：
10.1002/hlca.200390300
复制
发表时间：
2003-01-01
影响因子：
1.8
通讯作者：
Breslow, R
中科院分区：
文献类型：
--
作者：
Zhou, WJ;Liu, L;Breslow, R
Pyridoxamine was linked to a series of polyethylenimmes (PEls) with M-n = 600 1800, 10,000, and 60,000, both simply permethylated and with additional attached dodecyl chains. They were examined in the transamination of pyruvic acid and of phenylpyruvic acid, and showed Michaelis - Menten behavior. The values of k(2) and of K-M determined showed only small variations with polymer size. Thus, the previously reported strong advantage of pyridoxamines attached to the M-n = 60,000 PEI, relative to simple pyridoxamine alone, is seen to almost the same extent with the smaller PEIs.
