Investigation to Minimize Electrochemical Impedance Spectroscopy Drift.
Investigation to Minimize Electrochemical Impedance Spectroscopy Drift.
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DOI：
10.1149/09707.0737ecst
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Halpern JM
中科院分区：
文献类型：
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作者：
Ziino ER;Marnoto S;Halpern JM
电化学阻抗谱（EIS）是一种用于表征物理化学过程的技术，特别是在生物传感器领域。然而，众所周知，由于固有的漂移，EIS具有可重复性问题。当使用EIS对同一精确溶液进行重复测量时，阻抗测量具有增加的趋势，可以通过线性斜率详细说明。报告的EIS漂移范围为0.11至5.5 Ω/min。我们研究了漂移，以协助未来的数据解释和模型拟合。我们发现工作电极的清洁度和处理会影响EIS漂移，并且可以通过在重复运行之间冲洗工作电极来最小化漂移。
Electrochemical impedance spectroscopy (EIS) is a technique used to characterize physiochemical processes, especially in the field of biosensors. However, EIS has been known to have reproducibility issues due to an inherent drift. When taking repeated measurements of the same exact solution using EIS, impedance measurements have an increasing trend which can be detailed by a linear slope. The reported EIS drift ranges from 0.11 to 5.5 Ω/min. We studied the drift to assist with future data interpretation and model fitting. We discovered the cleanliness and treatment of the working electrode effects EIS drift, and the minimization of the drift can occur by rinsing the working electrode in-between repeated runs.