METHIONINE BIOSYNTHESIS IN SACCHAROMYCES-CEREVISIAE .1. GENETIC-ANALYSIS OF AUXOTROPHIC MUTANTS
METHIONINE BIOSYNTHESIS IN SACCHAROMYCES-CEREVISIAE .1. GENETIC-ANALYSIS OF AUXOTROPHIC MUTANTS
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DOI：
10.1007/bf00264692
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发表时间：
1975-01-01
期刊：
影响因子：
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通讯作者：
ROBICHONSZULMAJSTER, HD
中科院分区：
文献类型：
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作者：
MASSELOT, M;ROBICHONSZULMAJSTER, HD
为了分析Sacch中有多少结构基因参与了蛋氨酸生物合成的特定步骤。酿酒酵母中，通过互补研究了一百个突变体。将21个组定义为MET 1至MET 25。没有发现同一互补组的独立突变体之间的重组，也没有发现不同组之间的连锁。在生化研究的初步阶段，测试了每个互补组的突变体利用各种蛋氨酸前体的能力。
In order to analyse how many structural genes are implicated in the specifi steps of the biosynthesis of methionine inSacch. cerevisiae, a hundred mutants were studied by complementation. 21 groups were defined named MET1 to MET25. Neither recombination between independent mutants of the same complementation group nor linkage between different groups was found. Preliminary to biochemical studies, mutants of each complementation group were tested for their capacity to utilize various precursors of methionine.