THE EFFECT OF A 20-WEEK ENDURANCE TRAINING-PROGRAM ON ADIPOSE-TISSUE MORPHOLOGY AND LIPOLYSIS IN MEN AND WOMEN
THE EFFECT OF A 20-WEEK ENDURANCE TRAINING-PROGRAM ON ADIPOSE-TISSUE MORPHOLOGY AND LIPOLYSIS IN MEN AND WOMEN
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DOI：
10.1016/0026-0495(84)90043-x
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发表时间：
1984-01-01
影响因子：
9.8
通讯作者：
THERIAULT, G
中科院分区：
文献类型：
--
作者：
DESPRES, JP;BOUCHARD, C;THERIAULT, G
为探讨耐力训练对脂肪组织形态学和脂肪分解的影响，对22名成年受试者（男11名，女11名）进行了为期20周的运动训练，每周4-5天，每天40分钟，最大心率80%。在训练前后，他们在髂上区域进行脂肪组织活检。在分离的脂肪细胞上测定脂肪细胞重量（FCW）和脂解活性。对于整个样本，训练显着降低了FCW（前：0.40。+-。0.13（平均值±）。SD）与给药后：0.36 ±。0.13μ g; P < 0.05），脂肪百分比（前：22.0 ± 0.001），8.3与术后相比：19.7 .+-。8.1%; P < 0.05）和增加的脂肪细胞肾上腺素最大刺激脂解（ESL）（pre：1.08 . ±. 0.49与术后相比：1.69 .+-。0.67μ mol甘油/30分钟/106个细胞; P < 0.001）。未观察到脂肪细胞数量变化。然而，在女性中，训练没有引起健身指标（%脂肪，皮褶总和，FCW）的变化。运动计划显著降低了男性的肥胖率（%脂肪：P < 0.001;皮褶总数：P < 0.01; FCW：P < 0.05）。在两种性别中，在训练后观察到ESL显著增加。然而，男性的ESL比女性对培训的反应更好（女性的ESL：1.36 .+-. 0.67与男性ESL相比：2.02 .+-。0.50μ mol甘油/30分钟/106个细胞; P < 0.05），在女性和男性中分别比训练前值增加46%和66%。训练可以影响脂肪组织的形态和脂解，而且对训练的敏感性存在明显的性别差异。
In order to asess the effect of endurance training on adiose tissue morphology and lipolysis, 22 adult subjects (11 men and 11 women) took part in a 20-wk ergocyte training program, 4-5 days a wk, 40 min a day, at 80% of their maximal heart rate. Before and after training, they were submitted to an adipose tissue biopsy in the suprailiac region. Fat cell weight (FCW), and lipolytic activity were determined on isolated fat cells. For the whole sample, training significantly reduced FCW (pre: 0.40 .+-. 0.13 (mean .+-. SD) vs. post: 0.36 .+-. 0.13 .mu.g; P < 0.05), percentage of fat (pre: 22.0 .+-. 8.3 vs. post: 19.7 .+-. 8.1%; P < 0.05) and increased adipocyte epinephrine maximal stimulated lipolysis (ESL) (pre: 1.08 .+-. 0.49 vs. post: 1.69 .+-. 0.67 .mu.mol glycerol/30 min per 106 cells; P < 0.001). No changes were observed in fat cell number. In women, however, training induced no changes in the fitness indicators (% fat, sum of skinfolds, FCW). The exercise program significantly lowered the adiposity of men (% fat: P < 0.001; sum of skinfolds: P < 0.01; FCW: P < 0.05). In both sexes, a significant increase in ESL was observed after training. ESL of men, however, responded better than that of women to training (ESL of women: 1.36 .+-. 0.67 vs. ESL of men: 2.02 .+-. 0.50 .mu.mol glycerol/30 min per 106 cells; P < 0.05), with increases over pre-training values of 46% and 66% in women and men, respectively. Training can influence adipose tissue morphology and lipolysis and apparently there is a sex difference in the sensitivity to training.