Diffusion weighted imaging in the liver
Diffusion weighted imaging in the liver
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DOI：
10.3748/wjg.v16.i13.1567
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发表时间：
2010-04-07
影响因子：
4.3
通讯作者：
van der Jagt, Eric J.
中科院分区：
文献类型：
--
作者：
Kele, Petra G.;van der Jagt, Eric J.
扩散加权磁共振成像 (DWI) 是一种成像技术，通过测量组织内水分子的扩散特性来提供组织对比度。扩散以表观扩散系数 (ADC) 表示，反映了每种组织特有的扩散特性。 DWI 最初用于神经放射学。最近，除了传统的非增强和增强磁共振成像 (MRI) 之外，DWI 也越来越多地用于身体其他部位。造成这种延迟的原因是该技术固有的一些技术问题，使得 DWI 对伪影非常敏感，必须克服这些问题。通过评估 ADC 值，DWI 被证明有助于表征肝脏局灶性病变。然而，DWI 应始终与常规 MRI 结合使用，因为良性和恶性病变的 ADC 值之间存在相当大的重叠。 DWI 可用于检测肝硬化肝中的肝细胞癌和检测肿瘤患者的肝转移。此外，DWI 是预测肿瘤对化疗的反应以及肿瘤患者治疗后随访的有前途的工具，因为 DWI 可能能够比传统成像更早地检测复发性疾病。本综述重点关注 DWI 在肝脏中最常见的应用。 (C)2010年百事登。版权所有。
Diffusion weighted magnetic resonance imaging (DWI) is an imaging technique which provides tissue contrast by the measurement of diffusion properties of water molecules within tissues. Diffusion is expressed in an apparent diffusion coefficient (ADC), which reflects the diffusion properties unique to each type of tissue. DWI has been originally used in neuroradiology. More recently, DWI has increasingly been used in addition to conventional unenhanced and enhanced magnetic resonance imaging (MRI) in other parts of the body. The reason for this delay was a number of technical problems inherent to the technique, making DWI very sensitive to artifacts, which had to be overcome. With assessment of ADC values, DWI proved to be helpful in characterization of focal liver lesions. However, DWI should always be used in conjunction to conventional MRI since there is considerable overlap between ADC values of benign and malignant lesions. DWI is useful in the detection of hepatocellular carcinoma in the cirrhotic liver and detection of liver metastases in oncological patients. In addition, DWI is a promising tool in the prediction of tumor responsiveness to chemotherapy and the follow-up of oncological patients after treatment, as DWI may be capable of detecting recurrent disease earlier than conventional imaging. This review focuses on the most common applications of DWI in the liver. (C) 2010 Baishideng. All rights reserved.