Comparison of left ventricular function by tissue Doppler imaging in patients with diabetes mellitus without systemic hypertension versus diabetes mellitus with systemic hypertension
Comparison of left ventricular function by tissue Doppler imaging in patients with diabetes mellitus without systemic hypertension versus diabetes mellitus with systemic hypertension
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DOI：
10.1016/j.amjcard.2004.04.048
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发表时间：
2004-08-01
影响因子：
2.8
通讯作者：
Mazurek, W
中科院分区：
文献类型：
--
作者：
Kosmala, W;Kucharski, W;Mazurek, W
由于糖尿病可显著增加心力衰竭的发生风险，我们试图在合并或不合并全身性高血压的糖尿病患者中建立左心室收缩和舒张功能的早期改变。我们研究了134名受试者使用超声心动图，包括标准的二维和常规多普勒以及组织多普勒成像。我们的研究表明，早期出现的左心室收缩和舒张功能不全的糖尿病患者在休息和糖尿病的贡献的影响，心肌损害产生的高血压，以及组织多普勒成像在检测和定量糖尿病患者的心肌功能不全。该方法上级优于其他超声心动图技术和血浆脑钠肽评价。（C）2004年由Excerpta Medica，Inc.
Because diabetes mellitus substantially increases the risk of development of heart failure, we sought to establish early alterations in left ventricular systolic and diastolic function in patients with diabetes mellitus with and without coexisting systemic hypertension. We studied 134 subjects using echocardiography comprising standard 2-dimensional and conventional Doppler as well as tissue Doppler imaging. Our study demonstrated the early appearance of both left ventricular systolic and diastolic dysfunction in diabetic patients at rest and the contributory effects of diabetes to myocardial impairment produced by hypertension, as well as the high usefulness of tissue Doppler imaging in detection and quantitation of myocardial dysfunction in diabetics. This method was superior to other echocardiographic techniques and plasma brain natriuretic peptide evaluation. (C)2004 by Excerpta Medica, Inc.