Outcomes of laparoscopic sleeve gastrectomy in elderly obese Japanese patients.
Outcomes of laparoscopic sleeve gastrectomy in elderly obese Japanese patients.
复制标题
日本老年肥胖患者腹腔镜袖状胃切除术的结果。
DOI：
10.1111/ggi.13022
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Yokote K.
中科院分区：
文献类型：
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作者：
Hayashi A;Maeda Y;Takemoto M;Tokuyama H;Koide H;Kitahara A;Hayashi H;Kitamoto T;Yamaga M;Kobayashi K;Yokote K.
目的腹腔镜袖状胃切除术（LSG）已被证明是治疗病态肥胖最有效的策略，但其在老年人群中的有效性和安全性尚未得到证实。在这项研究中，我们评估了LSG在日本老年肥胖患者中的有效性和安全性。方法选取3例50 ~ 60岁的肥胖者和11例60岁以下的肥胖者行LSG。检查至少12个月后的术前和术后变化，包括体重、体重指数、总体重减轻、超重减轻、骨密度和骨相关指标。结果<60岁和bbb60岁患者的总减重百分比（分别为24.4±11vs23±4.4%）和超重减重百分比（分别为49.1±23.4vs47.6±10%）差异无统计学意义。在LSG术前和术后12个月进行双能X射线吸收测定。两组腰椎、股骨颈骨密度变化差异无统计学意义（分别为0.01±0.06vs0.02±0.03 g/cm2、- 0.03±0.06vs - 0.08±0.02 g/cm2）。无围手术期和术后并发症。所有3例年龄在bb0 ~ 60岁的患者在LSG后股骨颈骨密度降低；其中一人被诊断患有骨质疏松症。结论：虽然目前的研究结果表明，LSG对老年肥胖日本患者有相当大的益处，但减肥手术后长期仔细观察对老年患者预防未来骨质疏松尤为重要。Geriatr Gerontol Int 2017；17: 2068 - 2073。
AimLaparoscopic sleeve gastrectomy (LSG) has proven to be the most effective strategy for the treatment of morbid obesity, however its efficacy and safety in an aging population has not yet been confirmed. In this study, we evaluated the effectiveness and safety of LSG in elderly obese Japanese patients.MethodsThree obese individuals aged >60 years and 11 obese individuals aged <60 years who underwent LSG were enrolled. Pre‐ and postoperative changes after at least 12 months were examined, including bodyweight, body mass index, total weight loss, excess weight loss, bone mineral density and bone‐related markers.ResultsThere were no significant differences between patients aged <60 years and >60 years in terms of percent total weight loss (24.4 ± 11vs23 ± 4.4%, respectively) and percent excess weight loss (49.1 ± 23.4vs47.6 ± 10 %, respectively). Dual‐energy X‐ray absorptiometry was carried out before and 12 months after LSG. There were no significant differences in bone mineral density changes at the lumbar spine and femoral neck between the two groups (0.01 ± 0.06vs0.02 ± 0.03 g/cm2, −0.03 ± 0.06vs−0.08 ± 0.02 g/cm2, respectively). There were no peri‐ and postoperative complications. All three patients aged >60 years had reduced bone mineral density in the femoral neck after LSG; one was diagnosed with osteoporosis.ConclusionsAlthough the present results suggest that LSG could be of considerable benefit to elderly obese Japanese patients, long‐term careful observation after bariatric surgery is especially important in elderly patients to prevent future osteoporosis.Geriatr Gerontol Int 2017; 17: 2068–2073.