Acceptability and feasibility of medical abortion in Nepal

Acceptability and feasibility of medical abortion in Nepal
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DOI:
10.1016/j.ijgo.2009.02.007
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发表时间:
2009-07-01
影响因子:
3.8
通讯作者:
Winikoff, Beverly
Winikoff, Beverly
中科院分区:
医学4区
文献类型:
--
作者:
Karki, Chanda;Pokharel, Hanoon;Winikoff, Beverly

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目的:在尼泊尔的2家三级教学医院和2家计划生育诊所测试米非司酮-米索前列醇简化方案用于早期流产的可行性和可接受性。研究方法:闭经56天或更短时间寻求终止妊娠的孕妇(n = 400)接受200 mg口服米非司酮,48小时后口服400 μ g米索前列醇,在家中或诊所给药。收集前瞻性数据,以确定妇女的经验,流产结果,并提供该方法的操作要求。结果:在367例已知结局的妇女中,大多数(91.3%)药物流产成功。如果有选择,大多数(89.7%)妇女选择在家服用米索前列醇。结论:在尼泊尔,一项简化的药物流产规程,包括米索前列醇的家庭给药,可以成功地纳入临床服务,尼泊尔最近使流产服务合法化。(C)2009年国际妇产科联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: To test the feasibility and acceptability of a simplified mifepristone-misoprostol regimen for early abortion in 2 tertiary teaching hospitals and 2 family planning clinics in Nepal. Methods: Consenting pregnant women (n = 400) with amenorrhea of 56 days or less seeking termination of pregnancy received 200 mg of oral mifepristone followed 48 hours later with 400 mu g of oral misoprostol, administered either at home or at the clinic. Prospective data were collected to determine the women's experience, abortion Outcome, and the operational requirements for providing the method. Results: Most (91.3%) of the 367 women with known outcomes had successful medical abortions. Given the option, most (89.7%) women elected to administer the misoprostol at home. Conclusion: A simplified medical abortion protocol, including home administration of misoprostol, can be Successfully integrated into clinical services in Nepal, where abortion services were recently legalized. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.