Language lateralization of Chinese-English bilingual patients with temporal lobe epilepsy: A functional MRI study
Language lateralization of Chinese-English bilingual patients with temporal lobe epilepsy: A functional MRI study
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DOI：
10.1037/0894-4105.20.5.589
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发表时间：
2006-09-01
期刊：
影响因子：
2.4
通讯作者：
Lam, Joseph M. K.
中科院分区：
文献类型：
--
作者：
Cheung, Mei-chun;Chan, Agnes S.;Lam, Joseph M. K.
本文应用功能磁共振成像（Functional MRI）技术，对汉英双语颞叶癫痫（TLE）患者的汉字和英语词的语言偏侧化进行了研究。结果表明，正常对照组在阅读英语单词时呈现左半球偏侧化，而在阅读汉字时呈现双半球偏侧化。中文和英文处理的神经基础的这种差异被发现影响与TLE相关的语言变化处理模式。也就是说，左侧TLE患者比右侧TLE患者更可能在阅读英语时表现出双半球语言参与，而左侧和右侧TLE患者在阅读汉字时表现出主要的双半球参与。
Functional MRI was used to examine language lateralization of Chinese characters and English words associated with temporal lobe epilepsy (TLE) in Chinese-English bilinguals with left or right TLE. The results suggest that the neural basis of processing Chinese and English seems to be different, as normal controls demonstrated left hemispheric lateralization in reading English words but bi-hemispheric lateralization in reading Chinese characters. This difference in the neural bases of Chinese and English processing was found to affect the patterns in change-of-language processing associated with TLE. That is, whereas left-TLE patients were more likely than right-TLE patients to demonstrate a bi-hemispheric language involvement in reading English, both left- and right-TLE patients demonstrated primarily bilateral hemispheric involvement for reading Chinese characters.