A multicenter study of outcome in systemic lupus erythematosus. II. Causes of death.
A multicenter study of outcome in systemic lupus erythematosus. II. Causes of death.
复制标题
系统性红斑狼疮结局的多中心研究。
作者：
Steven Rosner;E. Ginzler;E. Ginzler;H. Diamond;Max Weiner;Michael Schlesinger;J. Fries;C. Wasner;T. Medsger;G. Ziegler;J. Klippel;N. Hadler;D. Albert;E. Hess;G. Spencer;A. Grayzel;D. Worth;B. Hahn;E. Barnett
1965年至1978年，在参与狼疮生存研究小组的9个中心对1，103名系统性红斑狼疮患者进行了死亡原因检查。共有222名患者（20%）死亡。狼疮相关器官系统受累（主要是活动性肾炎）和感染是最常见的主要死亡原因。在整个随访期间，死亡原因相似。血液透析对肾炎患者的生存时间影响不大。活动性中枢神经系统疾病和心肌梗死是罕见的死亡原因。无恶性肿瘤死亡。
Causes of death were examined for 1,103 systemic lupus erythematosus patients who were followed from 1965 to 1978 at 9 centers that participated in the Lupus Survival Study Group. A total of 222 patients (20%) died. Lupus-related organ system involvement (mainly active nephritis) and infection were the most frequent primary causes of death. Causes of death were similar throughout the followup period. Hemodialysis had little impact on the length of survival for patients with nephritis. Active central nervous system disease and myocardial infarction were infrequent causes of death. There were no deaths from malignancy.