Vaccine effectiveness for laboratory-confirmed influenza in children 6-59 months of age, 2005-2007.
Vaccine effectiveness for laboratory-confirmed influenza in children 6-59 months of age, 2005-2007.
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DOI：
10.1016/j.vaccine.2011.09.037
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发表时间：
2011-11
期刊：
影响因子：
5.5
通讯作者：
M. Staat;M. Griffin;Stephanie Donauer;K. Edwards;P. Szilagyi;G. Weinberg;C. Hall;M. Prill;S. Chaves;C. Bridges;K. Poehling;G. Fairbrother
中科院分区：
文献类型：
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作者：
M. Staat;M. Griffin;Stephanie Donauer;K. Edwards;P. Szilagyi;G. Weinberg;C. Hall;M. Prill;S. Chaves;C. Bridges;K. Poehling;G. Fairbrother
为了评估流感疫苗对实验室确诊的幼儿流感就诊的有效性，我们在2005-2007年患有急性呼吸道疾病或发烧的儿童中进行了配对病例对照研究。流感疫苗有效性（VE）是用实验室确诊的流感病例和流感检测呈阴性的对照组来计算的。流感疫苗在6-59月龄的完全接种儿童中的有效性为56% (95% CI: 25%-74%)；部分接种未发现显著VE。
To estimate the effectiveness of influenza vaccine against medical care visits for laboratory-confirmed influenza in young children we conducted a matched case–control study in children with acute respiratory illness or fever from 2005–2007. Influenza vaccine effectiveness (VE) was calculated using cases with laboratory-confirmed influenza and controls who tested negative for influenza. The effectiveness of influenza vaccine in fully vaccinated children 6–59 months of age was 56% (95% CI: 25%–74%); a significant VE was not found for partial vaccination.