Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges.
Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges.
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电子鼻技术鉴定中药材：应用与挑战
DOI：
10.3390/s17051073
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发表时间：
2017-05-09
期刊：
影响因子：
--
通讯作者：
He J
中科院分区：
文献类型：
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作者：
Zhou H;Luo D;GholamHosseini H;Li Z;He J
本文综述了近年来机器嗅觉在中草药鉴别中的应用。由于中草药种类繁多，生长来源复杂，成分规格多样，中草药的质量控制是一个具有挑战性的问题。大量研究表明，电子鼻作为一种先进的机器嗅觉系统，可以通过识别中草药的复杂气味来克服这一挑战。电子鼻技术具有实用性强、灵敏度高、实时检测和无损检测等特点，与气相色谱-质谱联用（GC-MS）等分析技术相比，表现出了更好的性能。虽然电子鼻技术在其他方面的应用有了很大的发展，但电子鼻在中药质量控制方面的应用报道有限。目前的研究的目的是审查的实际实施和优势的电子鼻稳健和有效的气味识别中草药。它涵盖了使用电子鼻技术来研究种植区域，识别方法，生产程序和储存时间对中草药的影响。此外，电子鼻的CHM识别的挑战和应用进行了研究。随着电子鼻技术的发展，气味有可能成为中药质量控制和药物研发的一个新的定量指标。会议还发现，在气味标准化和气味再现遥感领域还可以开展更多的研究。
This paper provides a review of the most recent works in machine olfaction as applied to the identification of Chinese Herbal Medicines (CHMs). Due to the wide variety of CHMs, the complexity of growing sources and the diverse specifications of herb components, the quality control of CHMs is a challenging issue. Much research has demonstrated that an electronic nose (E-nose) as an advanced machine olfaction system, can overcome this challenge through identification of the complex odors of CHMs. E-nose technology, with better usability, high sensitivity, real-time detection and non-destructive features has shown better performance in comparison with other analytical techniques such as gas chromatography-mass spectrometry (GC-MS). Although there has been immense development of E-nose techniques in other applications, there are limited reports on the application of E-noses for the quality control of CHMs. The aim of current study is to review practical implementation and advantages of E-noses for robust and effective odor identification of CHMs. It covers the use of E-nose technology to study the effects of growing regions, identification methods, production procedures and storage time on CHMs. Moreover, the challenges and applications of E-nose for CHM identification are investigated. Based on the advancement in E-nose technology, odor may become a new quantitative index for quality control of CHMs and drug discovery. It was also found that more research could be done in the area of odor standardization and odor reproduction for remote sensing.