Near-infrared reflectance imaging in eyes with acute zonal occult outer retinopathy

Near-infrared reflectance imaging in eyes with acute zonal occult outer retinopathy
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急性区域性隐匿性外层视网膜病变眼的近红外反射成像

DOI:
10.1097/iae.0000000000000502
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发表时间:
2015
期刊:
Retina.
影响因子:
--
通讯作者:
Terasaki H.
Terasaki H.
中科院分区:
--
文献类型:
--
作者:
Ueno S;Kawano K;Ito Y;Ra E;Nakanishi A;Nagaya M;Terasaki H.

文献摘要

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目的:探讨近红外(IR)激光共聚焦扫描在急性带状隐匿性外视网膜病变(AZOOR)中的成像效果。方法:观察性病例系列。回顾10例AZOOR患者12只眼的病历。从AZOOR眼睛获得的扫描激光验光图像与光谱域光学相干断层扫描、眼底自体荧光和自适应光学眼底相机获得的图像进行了比较。结果:12只眼中有8只眼在红外图像上检测到异常低反射区,其余4只眼在红外图像上未见特异性异常。在光谱域光学相干层析成像中,异常低反射区域的边界与光感受器内段椭球带的不规则边界相对应。自适应光学眼底图像的锥体马赛克在红外图像的异常低反射区域被破坏。然而,眼底自身荧光异常区域与红外图像中的低反射区域不一致。结论:AZOOR患者红外图像出现低反射区提示光感受器区受损。红外图像对AZOOR的评价有一定的参考价值。
Purpose:To investigate the confocal scanning laser ophthalmoscopic images obtained with near-infrared (IR) light in eyes with acute zonal occult outer retinopathy (AZOOR).Methods:Observational case series. The medical records of 12 eyes of 10 patients with AZOOR were reviewed. Scanning laser ophthalmoscopic images obtained from the AZOOR eyes were compared with images obtained by spectral-domain optical coherence tomography, by fundus autofluorescence, and by an adaptive optics fundus camera.Results:In 8 of 12 eyes, abnormal hyporeflective areas were detected in the IR images, and the other 4 eyes did not have specific abnormalities in the IR images. The boundaries of the abnormal hyporeflective areas corresponded with the border of the irregularity of photoreceptor inner segment ellipsoid band in the spectral-domain optical coherence tomography images. The cone mosaics of the adaptive optics fundus image were disrupted in the abnormal hyporeflective area of the IR image. However, the areas of fundus autofluorescence abnormalities did not coincide with the hyporeflective areas in the IR images.Conclusion:The presence of hyporeflective areas in the IR images of patients with AZOOR suggests impairment of the photoreceptors area. The IR images would be useful to evaluate eyes with AZOOR.