Clinical usefulness of blenderized food for selenium deficiency in pediatric patients with severe motor and intellectual disabilities
Clinical usefulness of blenderized food for selenium deficiency in pediatric patients with severe motor and intellectual disabilities
复制标题
混合食品对严重运动和智力障碍儿科患者硒缺乏症的临床疗效
DOI：
10.1159/000525450
复制
发表时间：
2022
影响因子：
3.9
通讯作者：
Takaharu Oue
中科院分区：
文献类型：
--
作者：
Masahiro Zenitani;Satoko Nose;Takaharu Oue
引言本研究旨在评估混合食品（BF）对严重运动和智力障碍（SMID）儿科患者硒缺乏的预防或治疗效果。方法对所有连续40例接受营养评估的SMID儿科患者的病历进行回顾性回顾并比较两组：肠内配方奶粉（EF）组和BF提供总热量摄入10%以上的BF组。接下来，对第一次营养评估后新开始混合管喂养的缺硒患者，评估硒缺乏的改善情况和膳食内容的变化。结果BF组患者的缺硒发生率明显低于EF组患者，血清硒水平较高。在第一次营养评估后开始混合管喂养的所有 7 名缺硒患者中，第二次营养评估时血清硒水平显着升高，尽管总硒摄入量、EF 硒摄入量和总热量摄入量没有显着差异，而且事实上 EF 的热量摄入量显着降低。结论 BFs 联合喂养可用于预防和治疗儿科 SMID 患者的硒缺乏症。
IntroductionThis study aimed to assess the preventive or therapeutic effects of blenderized food (BF) on selenium deficiency in pediatric patients with severe motor and intellectual disabilities (SMID).MethodsThe medical records of all 40 consecutive pediatric patients with SMID who underwent nutritional assessment were retrospectively reviewed and compared between two groups: the enteral formula (EF) group and the BF group fed with BF providing more than 10% of total caloric intake. Next, for the selenium-deficient patients who were newly started on blenderized tube feeds after the first nutritional assessment, improvement of selenium deficiency and change of dietary contents were assessed.ResultsThe BF group patients had a significantly lower prevalence of selenium deficiency and higher serum selenium levels than the EF group patients. In all 7 selenium-deficient patients who started blenderized tube feeds after the first nutritional assessment, serum selenium levels were significantly increased at the second nutritional assessment, even though total selenium intake, selenium intake by EF, and total caloric intake did not differ significantly, and, in fact, caloric intake was significantly decreased by EF.ConclusionCombined feeding of BFs can be useful for prevention and therapy of selenium deficiency in pediatric SMID patients.