All Glioblastoma Are Not Equal: Distinct Spatial Immune Profiles Between De Novo and Recurrent Tumors.
All Glioblastoma Are Not Equal: Distinct Spatial Immune Profiles Between De Novo and Recurrent Tumors.
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所有胶质母细胞瘤都不相同:新发肿瘤和复发肿瘤之间不同的空间免疫特征。
DOI:
10.1158/2326-6066.cir-22-0400
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发表时间:
2022
影响因子:
10.1
通讯作者:
Lathia,JustinD
中科院分区:
文献类型:
--
作者:
Bayik,Defne;Lee,Juyeun;Lathia,JustinD
Lack of insight into the immunosuppressive microenvironment of glioblastoma (GBM) hinders successful application of immunotherapy. In this issue, Alanio and colleagues identify a distinct T-cell localization profile between recurrent andde novoGBM highlighting the importance of spatial heterogeneity and providing new avenues to explore to improve GBM outcome.See related article by Alanio et al., p. 800 (3).