INCREASED NOISE TRAUMA IN GUINEA-PIGS THROUGH MAGNESIUM-DEFICIENCY

INCREASED NOISE TRAUMA IN GUINEA-PIGS THROUGH MAGNESIUM-DEFICIENCY
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DOI:
10.1007/bf00454034
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发表时间:
1982-01-01
期刊:
ARCHIVES OF OTO-RHINO-LARYNGOLOGY-ARCHIV FUR OHREN-NASEN-UND KEHLKOPFHEILKUNDE
影响因子:
--
通讯作者:
DOMBROWSKI, M
DOMBROWSKI, M
中科院分区:
其他
文献类型:
--
作者:
ISING, H;HANDROCK, M;DOMBROWSKI, M

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在4周的噪音暴露[95 dB(A)]中,缺镁豚鼠的听力损失明显高于喂食富镁饮食的豚鼠。听力损失与淋巴周围Mg含量呈负相关(r = -0.86)。除了这种听觉效应外,细胞内Mg降低,心肌胶原蛋白增加,这两者都与听力损失有关,是由缺镁和噪声应激引起的。
Mg-deficient guinea pigs developed significantly increased hearing loss during 4 wk of noise exposure [95 dB(A)] as compared to animals fed a Mg-rich diet. The hearing loss was negatively correlated to the Mg content of the perilymph (r = -0.86). Besides this auditory effect, there was a decrease of intracellular Mg and an increase of collagen in the myocardium, both of which were correlated to the hearing loss and caused by Mg deficiency and noise stress.