Attitudes Toward and Beliefs in the Effectiveness of Biomedical HIV Prevention Strategies Among Emerging and Young Adult Sexual Minority Men.
Attitudes Toward and Beliefs in the Effectiveness of Biomedical HIV Prevention Strategies Among Emerging and Young Adult Sexual Minority Men.
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新兴和年轻性少数男性对生物医学艾滋病毒预防策略有效性的态度和信念。
DOI：
10.1007/s12529-023-10244-4
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发表时间：
2023
影响因子：
2.7
通讯作者：
Horvath,KeithJ
中科院分区：
文献类型：
--
作者：
Ma,Junye;Chase,GregoryE;Black,Ashley;Klaphake,Jonathan;Garcia-Myers,Kelly;Baker,JasonV;Horvath,KeithJ
背景暴露前预防 (PrEP) 和 HIV 治疗作为预防是不可检测 = 不可传播 (U = U) 运动的基础，是性少数男性 (SMM) 预防 HIV 的两种有效生物医学方法。 SMM 新兴成年人（EA：18-24 岁）和年轻人（YA：25-29 岁）对 PrEP 和 U = U 的态度可能有所不同，从而导致性行为差异。然而，迄今为止，很少有研究评估 YA 和 EA 对 PrEP 和 U = U 有效性的信念差异程度。方法美国 80 名 SMM 的全国样本（Mage= 25.1 岁；53.7% 种族/族裔少数；38.8% EA；61.3% YA）参加了为期 6 个月的移动健康干预，以提高 PrEP 依从性。非参数测试使用基线数据评估了 EA 和 YA 之间性行为和对 PrEP 有效性的态度以及 U = U 的差异。结果与 EA 相比，较高比例的 YA 相信 PrEP 的有效性，并认为在采取 PrEP 后无需使用安全套。与 EA 相比，更多的 YA 愿意进行性行为，他们在了解 U = U 之前觉得风险太大，并且更愿意与 HIV 阳性伴侣进行无套性行为。相反，即使伴侣正在服用抗 HIV 药物，EA 也比 YA 更愿意使用安全套。 结论 总体而言，YAs 比 EA 更信任 U = U 和 PrEP 的有效性，这突显了 SMM 对生物医学 HIV 预防工具的看法存在发展差异。我们的研究结果强调了为 EA 和 YA 定制不同的艾滋病毒生物医学预防方案信息以优化吸收的重要性。
BackgroundPre-exposure prophylaxis (PrEP) and HIV treatment as prevention, which underlies the Undetectable = Untransmittable (U = U) campaign, are two effective biomedical approaches for HIV prevention among sexual minority men (SMM). Attitudes toward PrEP and U = U may differ between SMM emerging adults (EA: 18–24 years old) and young adults (YA: 25–29 years old) to drive differences in sexual behavior. However, to date, few studies assessed the degree to which YAs and EAs differ in their beliefs in the effectiveness of PrEP and U = U.MethodA national sample of 80 SMM in the USA (Mage= 25.1 years; 53.7% racial/ethnic minority; 38.8% EA; 61.3% YA) participated in a 6-month mHealth intervention for PrEP adherence. Non-parametric tests assessed differences in sexual behaviors and attitudes toward the effectiveness of PrEP and U = U between EAs and YAs using baseline data.ResultsCompared to EAs, higher proportions of YAs trusted PrEP’s effectiveness and considered condom use unnecessary after taking PrEP. More YAs than EAs were willing to engage in sexual behaviors that they felt too risky before learning about U = U and were more comfortable having condomless sex with HIV-positive partners. Conversely, a greater proportion of EAs than YAs preferred to use condoms even when their partners are on anti-HIV medications.ConclusionOverall, YAs trusted the effectiveness of U = U and PrEP more than EAs, underscoring developmental differences in SMM’s perspectives on biomedical HIV prevention tools. Our findings underscore the importance of tailoring messages on biomedical HIV prevention options differently for EAs and YAs to optimize uptake.