Nanoparticles in biomolecular detection
Nanoparticles in biomolecular detection
复制标题
DOI：
10.1016/s1748-0132(06)70020-2
复制
发表时间：
2006-02
期刊：
影响因子：
24.2
通讯作者：
N. Tansil;Zhiqiang Gao
中科院分区：
文献类型：
--
作者：
N. Tansil;Zhiqiang Gao
在生物分子检测中使用纳米颗粒作为标记物代替传统的分子荧光团已经导致灵敏度、选择性和多路复用能力的改进。然而，需要进一步简化，以将这些技术从实验室带到护理点。在这里，我们总结了使用纳米粒子作为标记，特别是在生物亲和传感器检测核酸和蛋白质的最新进展。
The use of nanoparticles as labels in biomolecular detection in place of conventional molecular fluorophores has led to improvements in sensitivity, selectivity, and multiplexing capacity. Nevertheless, further simplification is needed to take these technologies from the laboratory to point of care. Here, we summarize the latest developments in the use of nanoparticles as labels, especially in bioaffinity sensors for the detection of nucleic acids and proteins.