The Chiral SN Axis in Sulfenamides: Enantiomeric Resolution, Direct Demonstration of Optical Activity, and Kinetics of Interconversion†
The Chiral SN Axis in Sulfenamides: Enantiomeric Resolution, Direct Demonstration of Optical Activity, and Kinetics of Interconversion†
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亚磺酰胺中的手性 SN 轴：对映体拆分、光学活性的直接演示和相互转化的动力学†
DOI：
10.1002/anie.199722161
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发表时间：
1997
影响因子：
--
通讯作者：
D. Kost
中科院分区：
文献类型：
--
作者：
Merav Blanca;E. Maimon;D. Kost
在光学活性方面，首次证明了亚磺酰胺中仅由于SN键的限制转动所致的光学活性。通过选择性反相回收实验，测定了用高效液相色谱法分离的对映体(如下所示)的相互转化率。
Optically activity due only to restricted rotation about the S N bond in a sulfenamide is demonstrated for the first time. Selective inversion recovery experiments were utilized to measure the rate of interconversion of the enantiomers (shown below) that were seperated by using HPLC.