Perinadine A, a novel tetracyclic alkaloid from marine-derived fungus Penicillium citrinum
Perinadine A, a novel tetracyclic alkaloid from marine-derived fungus Penicillium citrinum
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DOI：
10.1021/ol051695h
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发表时间：
2005-09-15
期刊：
影响因子：
5.2
通讯作者：
Kobayashi, J
中科院分区：
文献类型：
--
作者：
Sasaki, M;Tsuda, M;Kobayashi, J
从金黄色青霉发酵液中分离得到一个新的四环生物碱Perinadine A(1)，其结构经二维核磁共振波谱数据确证。从生物遗传学上讲，Perinadine A(1)可能来自桔霉素(4)，一种众所周知的真菌毒素，以及一种鳞片酰胺A型吡咯烷生物碱。
A novel tetracyclic alkaloid, perinadine A (1), was isolated from the cultured broth of the fungus Penicillium citrinum, which was separated from the gastrointestine of a marine fish, and the structure was elucidated on the basis of spectroscopic data including 2D NMR spectra. Biogenetically, perinadine A (1) may be derived from citrinin (4), a well-known mycotoxin, and a scalusamide A-type pyrrolidine alkaloid.