Experimental infection of Phlebotomus perniciosus and determination of the natural infection rates of Leishmania infantum in dogs
Experimental infection of Phlebotomus perniciosus and determination of the natural infection rates of Leishmania infantum in dogs
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DOI：
10.1016/s0001-706x(00)00141-8
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发表时间：
2000-11-02
期刊：
影响因子：
2.7
通讯作者：
Castillo, JA
中科院分区：
文献类型：
--
作者：
Guarga, JL;Lucientes, J;Castillo, JA
用直接异种诊断法测定了12只感染婴儿利什曼原虫的狗的白蛉感染率，并根据临床症状进行了分类。将狗分为三个临床组，在它们之间没有观察到雌性白蛉感染率的统计学显著差异。这一结果表明了无症状和少症状犬的流行病学重要性。间接异种诊断使用以离体狗血为食的白蛉。该技术不能替代直接法用于检测被L.婴儿通过间接技术在动物血液中检测到的寄生虫数量增加并没有反映出疾病的临床恶化，因此拒绝将其用作疾病预后的指标。(C)2000 Elsevier Science B.V.保留所有权利。
Direct xenodiagnosis has been used to determine the infection rates in sand flies of 12 dogs parasitized by Leishmania infantum and classified in function of clinical signs. The dogs were divided into three clinical groups and no statistically significant differences in the infection rates of female sand flies were observed among them. This result indicates the epidemiological importance of asymptomatic and oligosymptomatic dogs. Indirect xenodiagnosis uses sand flies fed on the blood of dogs ex vivo. This technique was not found to be useful as an alternative to the direct method for the detection of dogs parasitized by L. infantum. The clinical worsening of the disease was not reflected in the increasing number of parasites detected in the animals' blood by the indirect technique, thereby rejecting its utility as an indicator of the prognosis of the disease. (C) 2000 Elsevier Science B.V. All rights reserved.