Fabrication of bimetallic microfluidic surface-enhanced Raman scattering sensors on paper by screen printing.
Fabrication of bimetallic microfluidic surface-enhanced Raman scattering sensors on paper by screen printing.
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DOI：
10.1016/j.aca.2013.07.017
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发表时间：
2013-08
影响因子：
6.2
通讯作者：
Lu-lu Qu;Qi-Xia Song;Yuanting Li;Mao-Pan Peng;Dawei Li;Li-Xia Chen;J. Fossey;Yitao Long
中科院分区：
文献类型：
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作者：
Lu-lu Qu;Qi-Xia Song;Yuanting Li;Mao-Pan Peng;Dawei Li;Li-Xia Chen;J. Fossey;Yitao Long
采用丝网印刷法在纤维素纸上制备了金-银微流控哑铃型表面增强拉曼散射（Sers）传感器。这些印刷传感器依赖于样品液滴注入区和哑铃图案两端的Sers检测区，通过以微米级精度连续印刷银纳米颗粒（Ag NP）和金纳米颗粒（Au NP）来制造。使用绝缘油墨图案化微流体通道以连接这两个区并形成疏水回路。由于纸在毫米大小的通道中的毛细作用，传感器可以实现流体的自过滤，以去除废水中的悬浮颗粒，而无需泵送。该传感器还允许灵敏的Sers检测，由于Ag NP的强表面增强和Au NP的优异化学稳定性的有利组合。以罗丹明6 G为探针研究了该传感器的Sers性能，检测限为1.1 × 10− 13 M，增强因子为8.6 × 106。此外，哑铃形SERS传感器表现出良好的稳定性，Sers性能在空气中保持超过14周，并且具有高再现性，点到点Sers强度的变化小于15%。利用该哑铃型双波长传感器，可以对废水样品中的取代芳烃污染物进行定量分析，表明其具有良好的现场快速痕量污染物检测能力，无需预先分离。
Au–Ag bimetallic microfluidic, dumbbell-shaped, surface enhanced Raman scattering (SERS) sensors were fabricated on cellulose paper by screen printing. These printed sensors rely on a sample droplet injection zone, and a SERS detection zone at either end of the dumbbell motif, fabricated by printing silver nanoparticles (Ag NPs) and gold nanoparticles (Au NPs) successively with microscale precision. The microfluidic channel was patterned using an insulating ink to connect these two zones and form a hydrophobic circuit. Owing to capillary action of paper in the millimeter-sized channels, the sensor could enable self-filtering of fluids to remove suspended particles within wastewater without pumping. This sensor also allows sensitive SERS detection, due to advantageous combination of the strong surface enhancement of Ag NPs and excellent chemical stability of Au NPs. The SERS performance of the sensors was investigated by employing the probe rhodamine 6G, a limit of detection (LOD) of 1.1 × 10−13M and an enhancement factor of 8.6 × 106could be achieved. Moreover, the dumbbell-shaped bimetallic sensors exhibited good stability with SERS performance being maintained over 14 weeks in air, and high reproducibility with less than 15% variation in spot-to-spot SERS intensity. Using these dumbbell-shaped bimetallic sensors, substituted aromatic pollutants in wastewater samples could be quantitatively analyzed, which demonstrated their excellent capability for rapid trace pollutant detection in wastewater samples in the field without pre-separation.