High body mass index and dietary pattern are associated with childhood asthma
High body mass index and dietary pattern are associated with childhood asthma
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DOI：
10.1002/ppul.20372
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发表时间：
2006-12-01
影响因子：
3.1
通讯作者：
Lee, Ha-Baik
中科院分区：
文献类型：
--
作者：
Hong, Soo-Jong;Lee, Moo-Song;Lee, Ha-Baik
哮喘患病率的增加与儿童和成人体重指数（BMI）的增加同时发生。我们调查了体重指数与哮喘症状患病率之间的关系以及饮食模式的可能影响。这是一项以社区为基础的横断面研究，对象为 24,260 名 6 至 12 岁的学童。使用由家长填写的国际哮喘和儿童过敏研究 (ISAAC) 问卷的韩国版来评估哮喘患病率和潜在的混杂因素。我们分析了BMI与哮喘症状之间的关系以及饮食模式的可能影响。在男孩中，高 BMI 与之前 12 个月的喘息患病率之间仍然存在显着的正相关性（调整后的比值比，1.610；95% 置信区间，1.274-2.033），但在女孩中则不然。此外，高 BMI 与终生喘息患病率、既往 12 个月喘息、运动诱发喘息、哮喘诊断和治疗之间存在显着相关性。无论是母乳喂养还是全脂奶喂养，高 BMI 与之前 12 个月的喘息之间存在显着相关性。经常摄入新鲜海鲜、新鲜水果和蔬菜与当前哮喘症状患病率降低相关，也与体重指数降低相关。这些结果表明，BMI可能是男孩出现哮喘症状的独立危险因素。摄入新鲜海鲜、新鲜水果和蔬菜可能与体重指数下降有关，可能有助于防止韩国小学生出现哮喘症状。
The increasing prevalence of asthma has coincided with an increase of body mass index (BMI) in both children and adults. We investigated the relationship between BMI and the symptom prevalence of asthma and the possible influences of dietary pattern. This was a community-based, cross-sectional study of 24,260 school children aged 6-12 years. Prevalences of asthma and potential confounding factors were assessed using a Korean version of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire which was completed by parents. We analyzed the relationship between BMI and symptoms of asthma and the possible influences of dietary pattern. A significant positive association between high BMI and previous 12-month prevalence of wheeze remained in boys (adjusted odds ratio, 1.610; 95% confidence interval, 1.274-2.033) but not in girls. In addition, there were significant associations between high BMI and lifetime prevalence of wheeze, previous 12-month wheeze, exercise-induced wheeze, diagnosis, and treatment of asthma. There were significant associations between high BMI and previous 12-month wheeze regardless of breast-milk feeding or whole-milk feeding. Frequent intake of fresh seafood, fresh fruits, and vegetables was associated with reduced prevalence of current asthma symptoms and was also associated with decreased BMI. These results indicate that BMI may be an independent risk factor for the development of asthma symptoms in boys. Intake of fresh seafood, fresh fruit, and vegetables, which may be associated with decreased BMI, may contribute to protect against the development of asthma symptoms in Korean elementary schoolchildren.