Real-Time Sonoelastography of Major Salivary Gland Tumors
Real-Time Sonoelastography of Major Salivary Gland Tumors
复制标题
DOI：
10.2214/ajr.11.6529
复制
发表时间：
2011-11-01
影响因子：
5
通讯作者：
Baciut, Grigore
中科院分区：
文献类型：
--
作者：
Dumitriu, Dana;Dudea, Sorin;Baciut, Grigore
OBJECTIVE.本研究的目的是确定实时超声弹性成像在涎腺肿瘤鉴别诊断中的作用。2007年至2010年间，对66例74个涎腺肿瘤患者进行了超声和声弹性成像检查。根据4分弹性成像评分对病变进行分级。所有病例均行手术切除和组织病理学检查。比较良恶性肿块、多形性腺瘤和Warthin瘤的弹性成像评分的差异。腮腺肿瘤63例，下颌下腺肿瘤11例。恶性肿瘤18例，良性肿瘤56例。多形性腺瘤的平均（+/- SD）弹性成像评分为2.58 ± 0.87，Warthin瘤为2.15 ± 0.80，其他良性肿瘤为2.00 ± 0.57，恶性肿瘤为2.94 ± 0.87。对于总体良性肿瘤，平均弹性成像评分为2.41 +/- 0.87。良性肿瘤与恶性肿瘤之间的弹性成像评分差异有统计学意义（p < 0.05），但恶性肿瘤与多形性腺瘤之间以及Warthin瘤与多形性腺瘤之间的差异无统计学意义。以2 ~ 3分和3 ~ 4分为界值，良性肿瘤与恶性肿瘤之间无统计学差异。虽然这项研究揭示了良性和恶性肿瘤之间的弹性成像评分的差异，详细的分析没有提供一致的结果。因此，实时超声弹性成像似乎是一个有限的技术之间的良恶性涎腺肿块的鉴别诊断。
OBJECTIVE. The purpose of this study was to determine the performance of real-time sonoelastography in the differential diagnosis of salivary gland tumors.SUBJECTS AND METHODS. Between 2007 and 2010, 74 salivary gland tumors were examined by ultrasound and sonoelastography in 66 patients. Lesions were graded according to a 4-point elastography score. Surgical excision and histopathologic examination were performed in all cases. The difference in elastographic score between benign and malignant masses and that between pleomorphic adenomas and Warthin tumors were evaluated.RESULTS. Of the 74 salivary tumors, 63 were located in the parotid, and 11 were in the submandibular gland. There were 18 malignant and 56 benign tumors. The mean (+/- SD) elastographic score was 2.58 +/- 0.87 for pleomorphic adenomas, 2.15 +/- 0.80 for Warthin tumors, 2.00 +/- 0.57 for other benign tumors, and 2.94 +/- 0.87 for malignant tumors. For benign tumors overall, the mean elastographic score was 2.41 +/- 0.87. The difference in elastographic score between benign and malignant tumors overall was statistically significant (p < 0.05), but the difference between malignant tumors and pleomorphic adenomas and that between Warthin tumors and pleomorphic adenomas were not statistically significant. Using cutoff values between scores 2 and 3 and scores 3 and 4, there was no statistically significant difference between benign and malignant tumors.CONCLUSION. Although this study revealed a difference in elastographic score between benign and malignant tumors, detailed analysis did not provide consistent results. Consequently, real-time sonoelastography appears to be a limited technique in the differential diagnosis between benign and malignant salivary masses.