In vitro inhibition of Toxoplasma gondii by four new derivatives of artemisinin
In vitro inhibition of Toxoplasma gondii by four new derivatives of artemisinin
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DOI：
10.1128/aac.00793-06
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发表时间：
2006-12-01
影响因子：
4.9
通讯作者：
Yolken, Robert
中科院分区：
文献类型：
--
作者：
Jones-Brando, Lorraine;D'Angelo, John;Yolken, Robert
Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is medically important and distributed worldwide. Currently available medications are limited in terms of efficacy and side effects. We synthesized novel, nonacetal, hydrolytically stable derivatives of artemisinin and showed that they inhibit the replication of Toxoplasma gondii in cell culture.
