FACTORS AFFECTING TRANSMISSION AND RECOVERY IN THE PASSIVE IRON NERVE MODEL.
FACTORS AFFECTING TRANSMISSION AND RECOVERY IN THE PASSIVE IRON NERVE MODEL.
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DOI：
10.1085/jgp.7.4.473
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发表时间：
1925-03-20
期刊：
影响因子：
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通讯作者：
Lillie RS
中科院分区：
文献类型：
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作者：
Lillie RS
1.活化波沿着封闭在含有稀硝酸（70%）的玻璃管中的无源铁丝的传输速度随电解质柱的电导率（截面积）而增加，但速率较慢。速度与电导率的平方根成正比。这种关系的原因进行了讨论，并提出了解释。2.在激活波通过后，transmittance的恢复是逐渐的，并遵循一个特征过程。在部分或递减传输的间隔（具有高温度系数并且在20°下持续几分钟）之后，导线恢复其将激活波传输无限距离的功率。在这种恢复的导线中，传输速度起初很慢，然后逐渐增加，直到达到最大值，这种增加遵循一条明显的曲线vt = v 0（1 - e_kt）。在不同温度下，达到最大值（相当于完全恢复）所需的近似时间为20°下15至20分钟，15°下30至45分钟，约。10°下60分钟，5°下90分钟或更长。3.恢复曲线的特征（将传输速度与自上次激活以来的间隔相关联的曲线）与以下假设一致：速度的增加取决于形成钝化膜的分子中的渐进化学变化，这种变化涉及（相对）非反应性分子转化为反应性分子，并遵循单分子反应的过程。4.传输速度的温度系数（在5°和20°之间）较低，约为Q 10 = 1.3至1.6。相反，恢复率的恢复率很高（Q 10 =约。3）。与神经和其他传递原生质系统中的条件的平行被指出和讨论。5.封闭在含酸的连续和间断玻璃管中的无源线浸入大量酸中，表现出远距离作用的特征现象;在适当的条件下，不同区域之间的活化影响的传输速度可以大大增加。特征的例子被引用，并指出一些可能的生理相似之处。
1. The speed of transmission of the activation wave along passive iron wires enclosed in glass tubes containing dilute (70 per cent) nitric acid increases with the conductivity (sectional area) of the column of electrolyte but at a slower rate. The speed is closely proportional to the square root of the conductivity See PDF for Equation. The reasons for this relationship are discussed and an explanation is proposed. 2. The recovery of transmissivity after the passage of an activation wave is gradual and follows a characteristic course. After an interval of partial or decremental transmission (having a high temperature coefficient and lasting several minutes at 20°), the wire recovers its power of transmitting an activation wave for an indefinite distance. In such a recovered wire the speed of transmission is at first slow and increases by degrees up to a maximum, the increase following a curve apparently of the type vt = v 0 (1 – e_kt). The approximate time required to attain this maximum (corresponding to complete recovery) at the different temperatures is 15 to 20 minutes at 20°, 30 to 45 minutes at 15°, ca. 60 minutes at 10°, and 90 minutes or more at 5°. 3. The character of the curve of recovery (the curve relating speed of transmission to interval since previous activation) agrees with the assumption that the increase in speed depends on a progressive chemical change in the molecules forming the passivating film, this change involving the transformation of (relatively) nonreactive into reactive molecules and following the course of a monomolecular reaction. 4. The temperature coefficient of the speed of transmission (between 5° and 20°) is low, of the order Q 10 = 1.3 to 1.6. That of the rate of recovery, on the contrary, is high (Q 10 = ca. 3). The parallel to the conditions in nerve and other transmitting protoplasmic systems is pointed out and discussed. 5. Passive wires enclosed in acid-containing continuous and interrupted glass tubes immersed in a large volume of acid exhibit characteristic phenomena of distance action; under appropriate conditions the velocity of transmission of the activating influence between different areas may thus be greatly increased. Characteristic instances are cited and some possible physiological parallels are pointed out.