Physiological and behavioral correlates of attention dysfunction in schizophrenic patients.

Physiological and behavioral correlates of attention dysfunction in schizophrenic patients.
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精神分裂症患者注意力功能障碍的生理和行为相关性。

DOI:
10.1016/0022-3956(78)90009-2
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发表时间:
1978
影响因子:
4.8
通讯作者:
M. H. Orzack
M. H. Orzack
中科院分区:
医学2区
文献类型:
--
作者:
C. Kornetsky;M. H. Orzack

文献摘要

被引文献

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进行了几项实验,以测试精神分裂症患者的许多行为缺陷可以归因于原发性注意力障碍和/或患者对玩调查人员的心理游戏普遍缺乏兴趣的提议。对连续操作测验(CPT)成绩好的精神分裂症患者(Gs)和表现不佳的精神分裂症患者(Ps)进行了反应时、CPT和EEG、慢波睡眠、环境和家庭预测因素的研究。SS包括123例慢性精神分裂症患者和18例正常对照(Cs)。结果如下:(A)P组的反应时明显慢于G组,后者明显慢于C组。(B)精神分裂症患者的β-2活性明显高于C组。(C)表现不佳预示着慢波睡眠的缺失。(D)在研究的精神分裂症患者中,有4人有精神病史,服用SS药物的患者家庭中精神疾病的发生率显著高于未服用药物的SS患者。(参考22)(心理信息数据库记录(C)2016 APA,版权所有)
Conducted several experiments to test the proposal that many of the behavioral deficits seen in schizophrenics can be accounted for by a primary attentional disorder and/or a general lack of interest by the patient in playing the psychological games of the investigator. Schizophrenics with good performance (Gs) on the Continuous Performance Test (CPT) were compared with those performing poorly (Ps) on it in studies of reaction time, CPT and EEG, slow-wave sleep, and environmental and familial predictors. Ss included a total of 123 chronic schizophrenics and 18 normal controls (Cs). Results are as follows:(a) The reaction time of the Ps was significantly slower than that of the Gs, who were significantly slower than the Cs.(b) Schizophrenics had significantly more beta-2 activity than did Cs.(c) Poor performance predicted the absence of slow-wave sleep.(d) 4 of the schizophrenics studied had a history of mental illness in the family, and medicated Ss had significantly more mental illness in the family than did unmedicated Ss.(22 ref)(PsycINFO Database Record (c) 2016 APA, all rights reserved)