Structure and function of the centriole in animal cells: Progress and questions

Structure and function of the centriole in animal cells: Progress and questions
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DOI:
10.1016/0962-8924(96)10033-7
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发表时间:
1996-09-01
影响因子:
19
通讯作者:
Gull, K
Gull, K
中科院分区:
生物学1区
文献类型:
--
作者:
Lange, BMH;Gull, K

文献摘要

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中心粒是许多真核细胞中公认的但知之甚少的细胞器。尽管电子显微镜对其基本的三重微管结构有很好的描述,但对其具体的分子组成几乎一无所知。在这里,Bodo Lange和基思Gull调查了细胞周期中的中心粒结构、复制和成熟,并将注意力集中在中心粒作为动物细胞中心体组成部分的可能作用和功能上。
The centriole is well-recognized, yet poorly understood organelle present in many eukaryotic cells. Despite excellent electron-microscopic descriptions of its basic triplet microtubule structure, almost nothing is known of its specific molecular components. Here, Bodo Lange and Keith Gull survey centriole structure, duplication and maturation within the cell cycle and focus attention on the possible roles and function of centrioles as components of the centrosome in animal cells.