Twelve hours is sufficient for social buffering of conditioned hyperthermia
Twelve hours is sufficient for social buffering of conditioned hyperthermia
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DOI：
10.1016/j.physbeh.2010.10.025
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发表时间：
2011-02-01
影响因子：
2.9
通讯作者：
Mori, Yuji
中科院分区：
文献类型：
--
作者：
Kodama, Yuka;Kiyokawa, Yasushi;Mori, Yuji
我们以前曾报道，在雄性大鼠，24小时的社会住房与关联的雄性大鼠后立即恐惧条件反射衰减条件性体温过高的听觉条件刺激。在这项研究中，我们调查的时间窗口和阈值的社会住房，“社会缓冲”减轻条件性体温过高。当6小时的社会住房后立即空调程序，衰减条件性高热没有发生。然而，18小时的社会住房期间，开始6小时后，空调程序成功地阻止了随后的高热，在我们以前的研究中观察到的。我们还缩短了社会住房的持续时间，发现12小时，但不是6小时，社会住房期间减轻了随后的体温过高。此外，一个24小时的社会住房期，开始后24小时的调节程序减轻了体温过高。这些结果表明，12小时是足够的社会缓冲的条件性高热。(C)2010年爱思唯尔公司All rights reserved.
We previously reported that in male rats, 24 h of social housing with an associate male rat immediately following fear conditioning attenuated conditioned hyperthermia in response to an auditory conditioned stimulus. In this study, we investigated the time window and threshold of social housing where "social buffering" mitigates conditioned hyperthermia. When 6 h of social housing immediately followed the conditioning procedure, attenuation of conditioned hyperthermia did not occur. However, an 18-h social housing period that started 6 h after the conditioning procedure successfully blocked the subsequent hyperthermia, as was observed in our previous study. We also shortened the duration of social housing and found that a 12-h, but not a 6-h, period of social housing mitigated the subsequent hyperthermia. In addition, a 24-h social housing period that started 24 h after the conditioning procedure mitigated the hyperthermia. These results suggest that 12 h is sufficient for social buffering of conditioned hyperthermia. (C) 2010 Elsevier Inc. All rights reserved.