Anxiety sensitivity and panic disorder

Anxiety sensitivity and panic disorder
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DOI:
10.1016/s0006-3223(02)01475-0
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发表时间:
2002-11-15
影响因子:
10.6
通讯作者:
McNally, RJ
McNally, RJ
中科院分区:
医学1区
文献类型:
--
作者:
McNally, RJ

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焦虑敏感性是指对与焦虑相关的感觉的恐惧。焦虑敏感性通常由焦虑敏感指数(ASI)来衡量,它是一种气质变量,在惊恐障碍患者中尤其偏高。不论是否确诊,ASI分数常常能预测在面对引发恐惧身体感觉的生理挑战(例如吸入二氧化碳)时的惊恐症状。前瞻性纵向研究表明,ASI分数可预测随后的自发性发作,这表明焦虑敏感性升高是惊恐发作以及可能是惊恐障碍的一个风险因素。认知行为疗法可降低惊恐障碍患者的焦虑敏感性,或许能防止复发。丙咪嗪同样可降低焦虑敏感性。(C)2002生物精神病学学会
Anxiety sensitivity refers to,fears of anxiety-related sensations. Most often measured by the Anxiety Sensitivity Index (ASI), anxiety sensitivity is a dispositional variable especially elevated in people with panic disorder. Regardless of diagnosis, ASI scores often predict panic symptoms in response to biological challenges (e.g., carbon dioxide inhalation) that provoke feared bodily sensations. Prospective longitudinal studies indicate that scores on the ASI predict subsequent spontaneous attacks, indicating that elevated anxiety sensitivity is a risk factor for panic and perhaps panic disorder. Cognitive behavioral treatment reduces anxiety sensitivity in panic patients, perhaps protecting against relapse. Imipramine likewise decreases anxiety sensitivity. (C) 2002 Society of Biological Psychiatry.