THE RADIAL ALVEOLAR COUNT METHOD OF EMERY AND MITHAL - A REAPPRAISAL .1. POSTNATAL LUNG GROWTH
THE RADIAL ALVEOLAR COUNT METHOD OF EMERY AND MITHAL - A REAPPRAISAL .1. POSTNATAL LUNG GROWTH
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DOI：
10.1136/thx.37.8.572
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发表时间：
1982-01-01
期刊：
影响因子：
10
通讯作者：
THURLBECK, WM
中科院分区：
文献类型：
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作者：
COONEY, TP;THURLBECK, WM
对76个正常产后肺重新评估了Emery和Mithal的径向肺泡计数方法。再现性评估的结果表明，每个观察员应建立正常的控制值时，开始的方法，并应随后使用控制情况下，以保持严格的再现性。使用10个视野/例不足以获得令人满意的再现性，即使对于单个观察者也是如此。先前的肺充气显著增加了径向计数，这一因素可能有助于解释本研究结果与Emery和Mithal结果之间的巨大差异。放射状计数与儿童的实际年龄有良好的相关性（r = +0.76; P < 0.001）。腺泡的肺泡化主要发生在出生到2岁之间;显著但较慢的生长在8岁之前，之后结果稳定，表明肺泡化完成。放射状计数法似乎提供了一个相对简单和合理满意的评估肺泡发育，最初提出的Emergy和Mithal。
The radial alveolar count method of Emery and Mithal was re-evaluated on 76 normal postnatal lungs. Results of reproducibility assessments suggest that each observer should establish normal control values when beginning with the method, and should subsequently use control cases to maintain strict reproducibility. The use of 10 fields/case was inadequate to obtain satisfactory reproducibility, even for a single observer. Prior inflation of the lungs significantly increased the radial counts and this factor may help to explain the large discrepancy between the results of this study and that of Emery and Mithal. The radial counts correlated well with the chronological age of the child (r = +0.76; P < 0.001). Alveolarization of the acinus occurs primarily between birth and 2 yr; significant but slower growth is seen up to 8 yr, after which the results plateau, suggesting that alveolarization is complete. The radial count method appears to provide a relatively simple and reasonably satisfatory assessment of alveolar development, as originally proposed by Emergy and Mithal.