Evaluation of regional wall motion and quantitative measures of ventricular function during dobutamine stress echocardiography in pediatric cardiac transplantation patients.
Evaluation of regional wall motion and quantitative measures of ventricular function during dobutamine stress echocardiography in pediatric cardiac transplantation patients.
复制标题
小儿心脏移植患者多巴酚丁胺负荷超声心动图期间局部室壁运动的评估和心室功能的定量测量。
DOI：
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复制
发表时间：
2000
影响因子：
6.5
通讯作者：
William B. Moskowitz
中科院分区：
文献类型：
--
作者：
M. Donofrio;Barham Kakavand;William B. Moskowitz
BACKGROUND
Graft coronary disease is a leading cause of death in patients who have undergone cardiac transplantation. The purpose of this study was to evaluate regional wall motion response and quantitative measures of ventricular function during dobutamine stress echocardiography (DSE) in pediatric transplantation patients.
METHODS
Eleven patients were evaluated the first year after transplantation (10/11 no rejection). Ten of the 11 were reevaluated 1.2 +/- 0.3 years later (9/10 no rejection).
RESULTS
Dobutamine stress echocardiography revealed the following: (1) baseline regional wall motion abnormalities in 80% that resolved in all, (2) increased heart rate and blood pressure, (3) no change in left ventricular end-diastolic diameter, (4) decreased end-systolic diameter, (5) decreased wall stress and increased velocity of circumferential fiber shortening, (6) increased VCFcZ score (representing systolic left ventricular function), and (7) a decreased mitral passive-to-active filling ratio. Patients with rejection had abnormal VCFcZ scores at rest.
CONCLUSIONS
Pediatric transplantation patients without rejection have baseline regional wall motion abnormalities. With DSE, the following are present: (1) resolution of wall motion abnormalities, (2) increased contractility independent of load, and (3) changes in diastolic parameters that reflect increased heart rate. Patients with rejection may have abnormal contractility at rest.
急性排斥反应期间同种异体心脏移植物的左心室功能：超声心动图评估。
DOI：
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发表时间：
1985
期刊：
The Journal of heart transplantation
影响因子：
--
作者：
Paulsen,W;Magid,N;Sagar,K;Hastillo,A;Wolfgang,TC;Lower,RR;Hess,ML
通讯作者：
Hess,ML
通过多巴酚丁胺负荷超声心动图无创检测移植冠状动脉疾病。
DOI：
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发表时间：
1994
期刊：
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
影响因子：
--
作者：
Akosah,KO;Mohanty,PK;Funai,JT;Jesse,RL;Minisi,AJ;Crandall,CW;Kirchberg,D;Guerraty,A;Salter,D
通讯作者：
Salter,D