EFFECTS OF A FISH OIL SUPPLEMENT ON PLATELET-FUNCTION, HEMOSTATIC VARIABLES AND ALBUMINURIA IN INSULIN-DEPENDENT DIABETICS
EFFECTS OF A FISH OIL SUPPLEMENT ON PLATELET-FUNCTION, HEMOSTATIC VARIABLES AND ALBUMINURIA IN INSULIN-DEPENDENT DIABETICS
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DOI：
10.1016/0049-3848(86)90101-5
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发表时间：
1986-09-15
影响因子：
7.5
通讯作者：
WALLACE, PG
中科院分区：
文献类型：
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作者：
HAINES, AP;SANDERS, TAB;WALLACE, PG
对41例胰岛素依赖型糖尿病患者每日服用15克鱼油补充剂(MaxEPA)对血脂、止血指标(包括血小板功能)和蛋白尿的影响进行了随机试验。与对照组相比，服用鱼油补充剂的组外周血小板胶原刺激产生的血栓素显着减少。血小板聚集的程度没有改变，但聚集前的滞后期延长。在服用鱼油补充剂的那一组中，血浆低密度脂蛋白胆固醇、纤维蛋白原和凝血因子X的水平也有统计上的显著上升。没有注意到其他显著差异。
A randomized trial of the effects of 15 gm per day of a fish oil supplement (MaxEPA) on blood lipids, haemostatic variables (including platelet function) and albuminuria was undertaken in 41 insulin dependent diabetics. Compared with the control group there was a significant reduction in thromboxane production by platelets stimulated by collagen in vitro in the group who took the fish oil supplement. The extent of platelet aggregation was not altered but the lag phase before aggregation was prolonged. There were also statistically significant increases in plasma LDL cholesterol, fibrinogen and clotting factor X in the group who took the fish oil supplement. No other significant differences were noted.