Monitoring external beam radiotherapy using real-time beam visualization
Monitoring external beam radiotherapy using real-time beam visualization
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DOI：
10.1118/1.4901255
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发表时间：
2015-01-01
期刊：
影响因子：
3.8
通讯作者：
Xing, Lei
中科院分区：
文献类型：
--
作者：
Jenkins, Cesare H.;Naczynski, Dominik J.;Xing, Lei
目的：描述一种新型放射治疗监测技术的性能，该技术利用柔性闪烁膜、普通光学探测器和用于实时光束可视化（RT-BV）的图像处理算法。方法：将Gd2O2S:Tb （GOS）与有机硅混合，在室温下浇铸形成闪烁薄膜。这些薄膜被放置在由医用直线加速器（LINAC）产生的治疗光束的路径上。发射的光随后被CMOS数码相机捕获。图像处理算法用于提取不同光束能量、剂量率和准直器位置下辐射场的强度、形状和位置。测量结果与已知的准直器设置进行了比较，以验证成像系统的性能。结果：RT-BV系统实现了足够的对比度-噪声比，能够在LINAC室内正常环境照明下以20 fps的速度实时监测LINAC光束。RT-BV系统成功地识别了亚毫米分辨率的准直器运动。结论：RT-BV系统能够以亚毫米精度定位放射治疗光束，并以视频速率照射跟踪光束运动。(c) 2015年美国医学物理学家协会。
Purpose: To characterize the performance of a novel radiation therapy monitoring technique that utilizes a flexible scintillating film, common optical detectors, and image processing algorithms for real-time beam visualization (RT-BV).Methods: Scintillating films were formed by mixing Gd2O2S:Tb (GOS) with silicone and casting the mixture at room temperature. The films were placed in the path of therapeutic beams generated by medical linear accelerators (LINAC). The emitted light was subsequently captured using a CMOS digital camera. Image processing algorithms were used to extract the intensity, shape, and location of the radiation field at various beam energies, dose rates, and collimator locations. The measurement results were compared with known collimator settings to validate the performance of the imaging system.Results: The RT-BV system achieved a sufficient contrast-to-noise ratio to enable real-time monitoring of the LINAC beam at 20 fps with normal ambient lighting in the LINAC room. The RT-BV system successfully identified collimator movements with sub-millimeter resolution.Conclusions: The RT-BV system is capable of localizing radiation therapy beams with sub-millimeter precision and tracking beam movement at video-rate exposure. (c) 2015 American Association of Physicists in Medicine.