Computed tomographic diagnosis of Mycobacterium avium-intracellulare complex in patients with bronchiectasis.
Computed tomographic diagnosis of Mycobacterium avium-intracellulare complex in patients with bronchiectasis.
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支气管扩张患者鸟分枝杆菌胞内复合体的计算机断层扫描诊断。
DOI：
10.1378/chest.105.1.49
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发表时间：
1994
期刊：
影响因子：
9.6
通讯作者：
David E. Williams
中科院分区：
文献类型：
--
作者：
S. Swensen;T. Hartman;David E. Williams
我们通过回顾100例CT诊断为支气管扩张的门诊患者的CT扫描和病史，验证了支气管扩张和胸部计算机断层扫描（CT）上显示的多个小肺结节表明鸟分枝杆菌-细胞内复合体（MAC）感染或定植的假设。在24例多发肺结节患者中，19例在同一肺叶有肺结节和支气管扩张。100例患者中63例进行了分枝杆菌培养，包括24例肺结节患者中的15例和76例无肺结节患者中的48例。在15例肺结节患者中，8例（53%）的MAC培养呈阳性，48例（4%）未发现肺结节的患者中有2例MAC培养呈阳性。在两组中，真菌培养阳性的数量大致相同。在我们的门诊人群中，CT预测支气管扩张患者多发小肺结节MAC培养阳性的敏感性为80%，特异性为87%，准确性为86%。
We tested the hypothesis that bronchiectasis and multiple small lung nodules seen on chest computed tomography (CT) are indicative of Mycobacterium avium-intracellulare complex (MAC) infection or colonization by reviewing CT scans and histories of 100 outpatients with CT diagnosis of bronchiectasis. Of the 24 patients with multiple pulmonary nodules, 19 had lung nodules and bronchiectasis in the same lobe. Mycobacterial cultures were performed on 63 of the 100 patients, including 15 of the 24 patients with lung nodules and 48 of the 76 patients with no lung nodules. Of the 15 patients with lung nodules, 8 (53 percent) had cultures positive for MAC, as did 2 of the 48 (4 percent) patients with no CT evidence of lung nodules. The number of cultures positive for fungi was approximately the same in both groups. In our outpatient population, CT prediction of cultures positive for MAC in bronchiectatic patients with multiple small lung nodules has a sensitivity of 80 percent, a specificity of 87 percent, and an accuracy of 86 percent.