Short-term skin reactions following use of N95 respirators and medical masks
Short-term skin reactions following use of N95 respirators and medical masks
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DOI：
10.1111/cod.13601
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发表时间：
2020-06-08
影响因子：
5.5
通讯作者：
Li, Li
中科院分区：
文献类型：
--
作者：
Hua, Wei;Zuo, Ying;Li, Li
研究背景在新冠肺炎疫情背景下，与佩戴口罩相关的皮肤不良反应病例不断出现。目的分析N95口罩和医用口罩对皮肤生理特性的短期影响，并报告防护设备引起的皮肤不良反应。方法本研究采用随机交叉设计，重复测量。招募20名健康中国志愿者。在戴上面罩后2和4小时以及取下面罩后0.5和1小时，在被相应面罩覆盖的区域和未覆盖的皮肤上测量皮肤参数，包括皮肤水合作用、经表皮水分损失（TEWL）、红斑、pH和皮脂分泌。不良反应进行了临床评估，并感知不适和不遵守measurement.Results皮肤水合作用，TEWL，和pH值显着增加与穿着防护设备。红斑值较基线增加。在穿戴设备的覆盖和未覆盖皮肤上的皮脂分泌增加。两种设备的生理值无显著差异。更多的不良反应报告后，使用N95口罩比使用医用口罩，具有较高的评分的不适和不合规.Conclusions这项研究表明，皮肤生物物理特性的变化，由于佩戴口罩或呼吸器。N95口罩比医用口罩引起更多的皮肤反应。
Background In the context of the COVID-19 pandemic, cases of adverse skin reactions related to the wearing of masks have been observed.Objectives To analyze the short-term effects of N95 respirators and medical masks, respectively, on skin physiological properties and to report adverse skin reactions caused by the protective equipment.Methods This study used a randomized crossover design with repeated measurements. Twenty healthy Chinese volunteers were recruited. Skin parameters were measured on areas covered by the respective masks and on uncovered skin 2 and 4 hours after donning, and 0.5 and 1 hour after removing the masks, including skin hydration, transepidermal water loss (TEWL), erythema, pH, and sebum secretion. Adverse reactions were clinically assessed, and perceived discomfort and non-compliance measured.Results Skin hydration, TEWL, and pH increased significantly with wearing the protective equipment. Erythema values increased from baseline. Sebum secretion increased both on the covered and uncovered skin with equipment-wearing. There was no significant difference in physiological values between the two types of equipment. More adverse reactions were reported following a N95 mask use than the use of a medical mask, with a higher score of discomfort and non-compliance.Conclusions This study demonstrates that skin biophysical characters change as a result of wearing a mask or respirator. N95 respirators were associated with more skin reactions than medical masks.