Walking training in postmenopause: effects on both spontaneous physical activity and training-induced body adaptations
Walking training in postmenopause: effects on both spontaneous physical activity and training-induced body adaptations
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DOI：
10.1097/gme.0b013e318223e6b3
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发表时间：
2012-01-01
影响因子：
2.7
通讯作者：
Napolitano, Giorgio
中科院分区：
文献类型：
--
作者：
Di Blasio, Andrea;Ripari, Patrizio;Napolitano, Giorgio
目的：由于体育锻炼已被广泛用于绝经后心脏代谢性疾病的一级和二级预防，本研究的目的是确定参加有氧体育锻炼是否与自发体力活动的改变有关，以及这种补偿是否影响有氧训练相关的身体适应。方法：对34名绝经后妇女(平均年龄+/-SD，55.89+/-3.57岁)在13周步行训练前后进行血脂、脂肪因子、血糖和胰岛素水平的分析，以及身体测量、安静时的心率和血压、最大有氧能力、每日总能量消耗、结果：有氧训练使大鼠的体质量、体质量指数、心率、收缩压、心脏基础乘积、血糖、瘦素、抵抗素等指标显著降低。有氧能力、心脏双倍体储备、定量胰岛素敏感指数均有明显改善。对每日总能量消耗、平均每日体力活动强度以及花费在强度超过3个代谢量的体力活动上的时间和能量的变化进行的聚类分析确定了两个亚组：一个亚组显示自发体力活动减少(组-)，而另一个亚组没有减少(组+)。各亚组之间仅在血脂变化方面存在显著差异。+组低密度脂蛋白胆固醇和总胆固醇显著降低，而-组血脂无明显变化。结论：绝经后参加有氧运动可导致自发性体力活动减少，从而抑制有氧运动对血脂和脂蛋白的积极作用。
Objective: Because physical exercise has been widely used for primary and secondary preventions of cardiometabolic diseases arising with menopause, the aim of our study was to determine whether participation in aerobic physical exercise is linked to the modification of spontaneous physical activity and whether this compensation affects aerobic training-related body adaptations.Methods: Both before and after a 13-week walking training program, 34 postmenopausal women (mean +/- SD age, 55.89 +/- 3.57 y) were analyzed for lipids, adipokines, glucose, and insulin plasma levels, as well as for body measures, heart rate and blood pressure at rest, maximal aerobic capacity, total daily energy expenditure, mean intensity of daily physical activities, and time and energy spent on physical activities with an intensity of more than three metabolic equivalents.Results: Aerobic training induced significant reductions in body mass, body mass index, heart rate, systolic blood pressure, basal cardiac double product, plasma glucose, leptin, and resistin. Aerobic fitness, the reserve of the cardiac double product, and the quantitative insulin sensitivity index were significantly improved. Cluster analysis of the variations in the total daily energy expenditure, the mean intensity of daily physical activities, and the time and energy spent on physical activities with an intensity of more than three metabolic equivalents identified two subgroups: one showed reduced spontaneous physical activity (GROUP-), whereas the other did not (GROUP+). The subgroups differed significantly only for plasma lipid variation. GROUP+ showed significantly reduced low-density lipoprotein cholesterol and total cholesterol, whereas GROUP- did not show significantly modified plasma lipids.Conclusions: In postmenopause, participation in a program of aerobic physical exercise can result in a reduction of spontaneous physical activity, which inhibits the positive effects of the aerobic exercise on plasma lipids and lipoproteins.