BRAIN-STEM AUDITORY-EVOKED RESPONSES - NORMAL VARIATION AS A FUNCTION OF STIMULUS AND SUBJECT CHARACTERISTICS
BRAIN-STEM AUDITORY-EVOKED RESPONSES - NORMAL VARIATION AS A FUNCTION OF STIMULUS AND SUBJECT CHARACTERISTICS
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DOI：
10.1001/archneur.1979.00500490037006
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发表时间：
1979-01-01
影响因子：
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通讯作者：
CORFITS, JL
中科院分区：
文献类型：
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作者：
STOCKARD, JE;STOCKARD, JJ;CORFITS, JL
脑干听觉诱发反应（BAER）引起的64个神经和听力正常的成年人和77个正常的，足月新生儿与宽带稀疏或冷凝点击在感觉水平（新生儿听力水平）30-70分贝和速度为10和80点击每秒。除了已知的影响率，以前未被认识到的影响，声相位和刺激强度对BAER峰间潜伏期（IPL），和所有3个刺激参数的相互作用，被发现。刺激的特点，年龄和性别可以解释大部分的间和受试者内变异的BAER IPL和形态。在BAER的临床应用中，许多这些变量的BAER效应及其相互作用尚未得到重视。识别和控制BAER变异性的这种可减少的方法学来源将提高神经系统诊断中测试的灵敏度和特异性。
Brainstem auditory-evoked responses (BAER) were elicited from 64 neurologically and audiometrically normal adults and 77 normal, full-term neonates with broadband rarefaction or condensation clicks at sensation levels (hearing levels in neonates) of 30-70 dB and at rates of 10 and 80 clicks per second. In addition to the known effects of rate, previously unrecognized effects of acoustic phase and stimulus intensity on BAER interpeak latencies (IPL), and an interaction of all 3 stimulus parameters, were found. Stimulus characteristics, age and sex can account for much of the inter- and intrasubject variability of BAER IPL and morphology. The BAER effects of many of these variables and their interactions have not been appreciated in clinical applications of BAER. Recognition and control of such reducible, methodological sources of BAER variability will enhance the sensitivity and specificity of the test in neurologic diagnosis.