Hydrostatic pressures in peritubular capillaries and tubules in the rat kidney.
Hydrostatic pressures in peritubular capillaries and tubules in the rat kidney.
复制标题
大鼠肾脏管周毛细血管和肾小管的静水压。
DOI：
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发表时间：
1971
影响因子：
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通讯作者：
R. Berliner
中科院分区：
文献类型：
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作者：
K. H. Falchuk;R. Berliner
库克湾H、和R. W.柏林。大鼠肾管周毛细血管和肾小管的静水压力。Am. J. Physiol.220（5）：1422-1426. 1971.采用微穿刺技术，利用伺服测压装置研究了肾皮质浅部小管和毛细血管内的压力关系。近端小管平均压力为10.9 ± 0.5 mm Hg，管周毛细血管平均压力为6.5 ± 0.5 mm Hg，远端小管平均压力为5.5 ± 0.4 mm Hg，星星血管平均压力为13.5 ± 0.8 mm Hg。输注等渗盐水、甘露醇或白蛋白溶液，或肾静脉部分收缩，或双侧颈动脉闭塞后，近端小管和管周毛细血管的压力均升高。主动脉部分收缩后，压力下降。在所有条件下，毛细血管和近端小管之间的压力差均存在。这些数据表明，肾皮质和间质空间的结构中的压力之间的关系是复杂的。这表明，肾皮质间质压低于以前认为的，可能不高于约5毫米汞柱。
FALCHUK, K. H., AND R. W. BERLINER. Hydrostatic pressures in peritubular capillaries and tubules in the rat kidney. Am. J. Physiol. 220(5) : 1422-1426. 197 1 .-A servo pressure-measuring device was used to study the pressure relationships in the tubules and capillaries of the superficial renal cortex by micropuncture techniques. Mean pressure was 10.9 =t 0.5 mm Hg in proximal tubules, 6.5 rt 0.5 mm Hg in peritubular capillaries, 5.5 rfr 0.4 mm Hg in distal tubules, and 13.5 =t 0.8 mm Hg in star vessels. Following infusions of isotonic saline, mannitol, or albumin solutions, or partial constriction of the renal vein, or occlusion of both carotids, the pressures in both proximal tubules and peritubular capillaries increased. Following partial constriction of the aorta, the pressures decreased. The difference in pressure between capillaries and proximal tubules was present under all conditions. These data suggest that the relationship between pressures in the structures of the renal cortex and the interstitial space is complex. It is suggested that renal cortical interstitial pressure is lower than previously believed, and probably no higher than about 5 mm Hg.