Childhood Periodic Syndromes: A Population-Based Study
Childhood Periodic Syndromes: A Population-Based Study
复制标题
DOI：
10.1016/j.pediatrneurol.2010.06.016
复制
发表时间：
2010-12-01
影响因子：
3.8
通讯作者：
Bigal, Marcelo E.
中科院分区：
文献类型：
--
作者：
Arruda, Marco A.;Guidetti, Vincenzo;Bigal, Marcelo E.
本研究的目的是评估与对照组受试者相比，偏头痛、偏头痛亚型和紧张型头痛儿童周期性综合征症状的患病率和相对风险。目标人口是在巴西一个城市就读公立小学的所有儿童(5-12岁)(n=2173)。获得同意的是1994名儿童；1906名儿童的可分析数据，1113名患有偏头痛、紧张型头痛或无头痛的儿童的最终样本。家长们使用有效的问卷进行了采访。头痛的诊断依据《国际头痛疾病分类》第二版。症状的相对风险是根据头痛类别相对于对照组得出的。对于发作性偏头痛，除夜间遗尿外，所有症状的相对风险显著增加：晕动病、复发性肢体疼痛、复发性腹痛和睡眠障碍，如梦话、梦游症和磨牙症。对于紧张型头痛，只有夜间遗尿和晕动感并不比对照组更常见。在多变量分析中，发作间期症状与头痛(P<；0.001)、偏头痛(P<；0.001)和紧张型头痛(P<；0.001)独立相关。这些发现表明，提示儿童周期性综合征的发作间歇期症状在人群中很常见，与偏头痛和特定的偏头痛亚型有关，但也与紧张型头痛有关。(C)2010，爱思唯尔公司。保留所有权利。
The objective of the present study was to estimate the prevalence and relative risk of symptoms suggestive of childhood periodic syndrome in migraine, migraine subtypes, and tension-type headache, relative to control subjects. The target population was all children (age 5-12 years) enrolled in public elementary schools in one Brazilian city (n = 2173). Consent was obtained for 1994 children; analyzable data were available for 1906 children, for a final sample of 1113 children with migraine, tension-type headache, or no headache. Parents were interviewed using validated questionnaires. Headache diagnosis was assigned according to the International Classification of Headache Disorders, 2nd edition. Relative risk of symptoms was drawn by headache categories relative to controls. For episodic migraine, the relative risk of all symptoms except nocturnal enuresis was significantly increased: motion sickness, recurrent limb pain, recurrent abdominal pain, and parasomnias, such as sleep talking, somnambulism, and bruxism. For tension-type headache, only nocturnal enuresis and motion sickness were not more common than in controls. In multivariate analyses, any interictal symptom was independently associated with any headache (P < 0.001), migraine headaches (P < 0.001), and tension-type headaches (P < 0.01). These findings indicate that interictal symptoms suggestive of childhood periodic syndromes are common in the population, and are associated with migraine and specific migraine subtypes, but also with tension-type headache. (C) 2010 by Elsevier Inc. All rights reserved.