Left-Liver Hypertrophy After Therapeutic Right-Liver Radioembolization Is Substantial but Less Than After Portal Vein Embolization
Left-Liver Hypertrophy After Therapeutic Right-Liver Radioembolization Is Substantial but Less Than After Portal Vein Embolization
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DOI：
10.1002/hep.26947
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发表时间：
2014-05-01
期刊：
影响因子：
13.5
通讯作者：
Seidensticker, Max
中科院分区：
文献类型：
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作者：
Garlipp, Benjamin;de Baere, Thierry;Seidensticker, Max
对于有可能接受扩大右肝切除术但残肝(FLR)大小不足的肝脏恶性肿瘤患者，携带肿瘤的肝脏的门静脉栓塞术(PVE)被用来诱导对侧肝肥大，但肿瘤不被治疗。放射栓塞术(RE)治疗栓塞的肺叶肿瘤，并诱导对侧肥大。我们进行了配对分析来比较这两种方式诱导肥厚的能力。在两个中心接受右叶PVE(n=141)或RE(n=35)治疗的无左肝肿瘤受累或可忽略的右肝继发性肝脏恶性肿瘤的患者，根据已知的影响PVE后肝再生的标准进行匹配：1)基线FLR/总肝体积比(
In patients with liver malignancies potentially amenable to curative extended right hepatectomy but insufficient size of the future liver remnant (FLR), portal vein embolization (PVE) of the tumor-bearing liver is used to induce contralateral liver hypertrophy but leaves the tumor untreated. Radioembolization (RE) treats the tumor in the embolized lobe along with contralateral hypertrophy induction. We performed a matched-pair analysis to compare the capacity for hypertrophy induction of these two modalities. Patients with right-hepatic secondary liver malignancies with no or negligible left-hepatic tumor involvement who were treated by right-lobar PVE (n=141) or RE (n=35) at two centers were matched for criteria known to influence liver regeneration following PVE: 1) baseline FLR/Total liver volume ratio (