Age at Immigration and Kidney Function among Self-Identified Healthy Africans in the United States.
Age at Immigration and Kidney Function among Self-Identified Healthy Africans in the United States.
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美国自我认定的健康非洲人的移民年龄和肾功能。
DOI：
10.1007/s10903-014-0138-0
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Sumner,AnneE
中科院分区：
文献类型：
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作者：
Ali,Mana;Mwendwa,DenéeT;Sims,Regina;Ricks,Madia;Sumner,AnneE
肾脏疾病严重影响非洲裔人。在美国总人口中，肾功能的年龄趋势已经普遍确定，但非洲移民移民时年龄的贡献尚不清楚。检查年龄和移民时年龄以及肾功能的独立和联合影响。计算了93名非洲移民（60%男性;平均年龄= 33.5岁）的估计肾小球滤过率（eGFR）。分层回归和事后分析显示，在考虑传统风险因素后，年龄×年龄在移民相互作用时，在年龄≤21岁的移民中。移民到美国时的年轻年龄可能会加剧自认为健康的非洲移民样本中年龄和肾功能之间的反比关系。调查与非洲移民肾脏健康相关的生物心理社会因素是必要的。
Kidney disease disparately affects those of African descent. Age trends have generally been established for kidney function in the overall US population, but the contribution of age at the time of immigration for African immigrants is unknown. To examine the independent and joint effects of age and age at the time of immigration, and kidney function. Estimated glomerular filtration rate (eGFR) was calculated for 93 African immigrants (60 % male; mean age = 33.5). Hierarchical regression and post hoc analyses revealed a significant age × age at the time of immigration interaction after accounting for traditional risk factors among those who immigrated at age ≤21. Younger age at the time of immigration to the US may exacerbate an inverse relationship between age and kidney function in a self-identified healthy African immigrant sample. Investigation of biopsychosocial factors associated with kidney health among African immigrants is warranted.