Studies on pathogenic and non-pathogenic small free-living amoebae and the bearing of nuclear division on the classification of the order amoebida.
Studies on pathogenic and non-pathogenic small free-living amoebae and the bearing of nuclear division on the classification of the order amoebida.
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致病性和非致病性小型自由生活阿米巴原虫的研究以及核分裂对阿米巴目分类的影响。
DOI：
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发表时间：
1970
期刊：
影响因子：
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通讯作者：
S. Das
中科院分区：
文献类型：
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作者：
B. Singh;S. Das
在标准化和可重复的培养条件下，对小型自由生活阿米巴进行了系统研究，并在小鼠中测试了其致病性。需氧耐格里菌（Naegleriaaerobia）、卡氏哈特曼氏菌（Hartmannellaculbertsoni）和H. rhysodes是致病的; H. castellanii，H. astronyxis，H. Palestinensis，巴氏黑腹蛛H. glycerin，H. exundans，H.蠕虫、裂核虫、杜氏双头螨和长喙四头螨是非致病性的。H. culbertsoni和H.在印度的土壤中也有纹石。本文将Amocbida肯特目分为裂核虫科、Hartmannellidae Volkonsky，1931. Singh，1952和Endamoebidae（Calkins）的分类，并讨论了这种分类与先前定义的变形虫科和属的关系及其对变形虫发生的影响。甲硝唑和其他抗阿米巴药物对N. aerobia和H. Culbertsoni体外和在小鼠脑膜脑炎中。
A systematic study of small free-living amoebae has been made under standardized and reproducible cultural conditions, and their pathogenicity has been tested in mice. Naegleria aerobia, Hartmannella culbertsoni and H. rhysodes are pathogenic; H. castellanii, H. astronyxis, H. palestinensis, H. glebae, H. exundans, H. vermiformis, Schizopyrenus russelli, Didascalus thorntoni and Tetramitus rostratus are non-pathogenic. Strains of H. culbertsoni and H. rhysodes are present in Indian soils. A classification of the order Amocbida Kent into families Schizopyrenidae Singh, Hartmannellidae Volkonsky, 1931 emend. Singh, 1952, and Endamoebidae (Calkins), based on nuclear division, is proposed, and the relation of this classification to previously defined families and genera of amoebae and its bearing on phylogeny are discussed. Metronidazole and other anti-amoebic drugs are ineffective against N. aerobia and H. culbertsoni in vitro and in meningo-encephalitis in mice.