Postcardiac arrest syndrome: focus on the brain.
Postcardiac arrest syndrome: focus on the brain.
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DOI：
10.1097/mop.0b013e328331e873
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发表时间：
2009-12
影响因子：
3.6
通讯作者：
Clark RS
中科院分区：
文献类型：
--
作者：
Manole MD;Kochanek PM;Fink EL;Clark RS
The field of pediatric cardiac arrest (CA) experienced recent advances secondary to multicenter collaborations. This review summarizes developments during the last year and identifies areas for further research. A large retrospective review demonstrated important differences in etiology, severity and outcome of in-hospital versus out-of-hospital pediatric CA. This distinction is relevant to interpretation of retrospective studies that may not distinguish between these entities, and in planning therapeutic clinical trials. Hypothermia was further evaluated as a treatment strategy after neonatal hypoxia and leaders in the field of neonatology recommend universal use of hypothermia in term neonates. In infants and children after CA, there are inadequate data to make a specific recommendation. Two retrospectives studies evaluating hypothermia in children after CA found that it tended to be administered more frequently to sicker patients. However, similar or worse outcomes of patients treated with hypothermia were observed. Use of extracorporeal membrane oxygenation (ECMO) is another emerging area of research in pediatric CA, and surprisingly good outcomes have been seen with this modality in some cases. Therapeutic hypothermia and ECMO continue to be the only treatment modalities over and above conventional care for pediatric CA. New approaches to monitoring, treatment and rehabilitation after CA remain to be explored.
