Isolation of azole-resistant Aspergillus fumigatus from imported plant bulbs in Japan and the effect of fungicide treatment
Isolation of azole-resistant Aspergillus fumigatus from imported plant bulbs in Japan and the effect of fungicide treatment
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DOI：
10.1584/jpestics.d20-017
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发表时间：
2020-01-01
影响因子：
2.4
通讯作者：
Hagiwara, Daisuke
中科院分区：
文献类型：
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作者：
Hagiwara, Daisuke
环境中越来越多的耐唑烟曲霉（ARAI）已成为全球公共卫生问题。我们对从荷兰进口的郁金香球茎进行了调查，发现 6.3-15.8% 的球茎受到 cyp51A 基因启动子区域串联重复突变的 ARAf 污染。我们还表明，用苯菌灵或咪鲜胺对郁金香球茎进行杀菌剂处理可有效降低分离率。这是第一份展示从植物球茎中消除人类真菌病原体的方法的报告。
Increasing numbers of azole-resistant Aspergillus fumigatus (ARAI) in the environment have become a global public health issue. We surveyed tulip bulbs that were imported from the Netherlands and found that 6.3-15.8% of bulbs were contaminated by ARAf with a tandem-repeat mutation in the promoter region of the cyp51A gene. We also showed that fungicide treatment of the tulip bulbs by benomyl or prochloraz effectively reduced the rate of isolation. This is the first report demonstrating a method of eliminating human fungal pathogens from plant bulbs.