Influence of nanomaterials on stem cell differentiation: designing an appropriate nanobiointerface.

Influence of nanomaterials on stem cell differentiation: designing an appropriate nanobiointerface.
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DOI:
10.2147/ijn.s29975
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发表时间:
2012
影响因子:
8
通讯作者:
Mocan L
Mocan L
中科院分区:
医学2区
文献类型:
--
作者:
Ilie I;Ilie R;Mocan T;Bartos D;Mocan L

文献摘要

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在过去的十年中,由于功能化化学的进步,已经开发了在组织工程和再生医学中应用的新型纳米生物材料。这些具有独特物理和化学性质的新型材料是具有生物活性的分级结构,对人体组织的未来发展具有很大的希望。因此,各种纳米材料目前正在深入探索干细胞的定向分化,新型生物活性支架的设计,以及组织再生的新研究途径。本文阐述了纳米技术在再生医学领域的组织工程应用的最新成果。
During the last decade, due to advances in functionalization chemistry, novel nanobiomaterials with applications in tissue engineering and regenerative medicine have been developed. These novel materials with their unique physical and chemical properties are bioactive hierarchical structures that hold great promise for future development of human tissues. Thus, various nanomaterials are currently being intensively explored in the directed differentiation of stem cells, the design of novel bioactive scaffolds, and new research avenues towards tissue regeneration. This paper illustrates the latest achievements in the applications of nanotechnology in tissue engineering in the field of regenerative medicine.