Controlled Studies on Women Presenting with Sexual Drive Disorder: I. Endocrine Status
Controlled Studies on Women Presenting with Sexual Drive Disorder: I. Endocrine Status
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对患有性欲障碍的女性的对照研究：I. 内分泌状况
DOI：
10.1080/00926230050084669
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发表时间：
2000
影响因子：
2.5
通讯作者：
A. Riley
中科院分区：
文献类型：
--
作者：
A. Riley
从15名终身性冲动缺失的绝经前女性患者和性冲动完整的对照组中获得了单次中期血液样本。测定血清睾酮、5-二氢睾酮（5-DHT）、17ß雌二醇、性激素结合球蛋白、催乳素水平，并计算游离睾酮和5-DHT指标。在获得血液样本的月经周期中，研究对象记录了他们的性欲和性活动。两组之间唯一显著不同的内分泌参数是游离睾酮，患者的游离睾酮水平低于对照组。研究了内分泌参数与性行为指标之间的关系。在对照组中，平均每日性念头与总睾酮、游离睾酮指数和游离5- DHT呈正相关。“性需求”感与游离5-DHT指数和游离睾酮指数呈正相关。性念头的经历与性需求相关，而手淫的平均频率与年龄负相关。在两组中，平均性交频率与游离睾酮指数相关。
A single mid-cycle blood sample was obtained from 15 premenopausal female patients presenting with lifelong absence of sexual drive and from a control group of women with intact sexual drive. Serum levels of testosterone, 5-dihydrotestosterone (5-DHT), 17ß oestradiol, sex hormone binding globulin, and prolactin were measured and indices of free testosterone and 5-DHT were derived. During the menstrual cycle in which the blood samples were obtained, the study subjects kept a diary of their sexual desire and activities. The only endocrine parameter that is significantly different between the two groups is free testosterone, which is lower in the patients than in the control women. Associations between endocrine parameters and indices of sexual behavior were examined. In the control group, average daily sexual thoughts correlates positively with total testosterone, free testosterone index, and free 5- DHT. Feeling of "need for sex" correlates positively with free 5-DHT index and free testosterone index. Experience of sexual thoughts correlates with need for sex, and average frequency of masturbation correlates negatively with age. In both groups, average coital frequency correlates with free testosterone index.
影响因子：
120.7
作者：
Laumann, EO;Paik, A;Rosen, RC
通讯作者：
Rosen, RC