Three-Dimensional Reconstitution of Cone Arrangement on the Spherical Surface of the Retina in the Medaka Eyes
Three-Dimensional Reconstitution of Cone Arrangement on the Spherical Surface of the Retina in the Medaka Eyes
复制标题
青鳉眼视网膜球面锥体排列的三维重建
DOI：
10.2108/zsj.14.795
复制
发表时间：
1997
影响因子：
--
通讯作者：
T. Morita
中科院分区：
文献类型：
--
作者：
Y. Nishiwaki;T. Oishi;F. Tokunaga;T. Morita
摘要青鳉视网膜中的四种视锥光感受器细胞排列成一种简单的、重复的组织模式，称为方形马赛克。我们发现，视网膜中视锥细胞的分布可以通过感光细胞的自发荧光发射轻易检测到，无需任何染色。在视网膜的切线切面上，视锥细胞位于晶格中的特定位置，如下所示：双视锥细胞对显示出一种重叠的外观，彼此之间大约成90-120度，而单视锥细胞位于由四个双视锥细胞对组成的正方形的中心。为了确定球面上这种规则排列的连续性，在视网膜的中央、背侧、腹侧、鼻侧和尾侧区域检查了这种锥形马赛克图案的分布。在整个视网膜中，锥细胞的排列是有规律的。双锥和单锥是在各自的线和这些线形成一个格子工作。在视网膜半球上重建这些排列的结果是，发现这种锥细胞网格的线条与视网膜边缘正交，从视网膜样子午线的中心辐射，并平行于视网膜边缘形成同心圆，这让人想起陆地地球仪的纵向和横向线条。青鳉整个视网膜中的视锥排列结构与生长期视网膜中的矩形镶嵌结构一致，新生细胞仅位于边缘细胞增殖区。
Abstract In the retina of the medaka four kinds of retinal cone photoreceptor cells are arranged in a simple, repeating organizational pattern known as a square mosaic. We found that the distribution of cones in the retina could be easily detected by autofluorescence-emission from the photoreceptor cells without any staining. In tangential sections of the retina, cones were located at a specific position in a crystalline lattice as follows: Double cone pairs display a zigzagging appearance, oriented roughly 90-120 degrees to one another, and single cones were in the center of the square consisting of four double cone pairs. In order to determine the continuity of this regular arrangement on the spherical surface, the distribution of this cone mosaic pattern was examined in central, dorsal, ventral, nasal and caudal areas of the retina. The regular arrangement of cones was confirmed in the whole retina. Double cones and single cones are in their respective lines and these lines form a lattice-work. As a result of reconstructing these arrangements on the retinal hemisphere, the lines of this lattice-work of cones were found to be orthogonal to the retinal margin, radiating from the center of the retina-like meridians, and parallel to the retinal margin forming concentric circles that is reminiscent of a longitudinal and a latitudinal lines of a terrestrial globe. This construction of the cone arrangement in whole retina of the medaka was consistent with maintaining a rectangular mosaic in growing retina with newly produced cells only in a marginal cell proliferating zone.
影响因子：
4.7
作者：
Godoy, Rafael;Noble, Sandra;Ekker, Marc
通讯作者：
Ekker, Marc