Pathology, cytogenetics and molecular biology of uterine leiomyomas and other smooth muscle lesions.
Pathology, cytogenetics and molecular biology of uterine leiomyomas and other smooth muscle lesions.
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子宫肌瘤和其他平滑肌病变的病理学、细胞遗传学和分子生物学。
DOI：
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发表时间：
1995
影响因子：
2.1
通讯作者：
B. Quade
中科院分区：
文献类型：
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作者：
B. Quade
子宫平滑肌肿瘤很常见，对育龄妇女构成严重的公共卫生问题。尽管大多数子宫平滑肌肿瘤是良性的，但罕见的恶性平滑肌肉瘤的病理诊断对于临床治疗和临床结果的预测很重要。对诊断子宫平滑肌肿瘤恶性肿瘤的病理标准及其有效性研究进行了综述。子宫肌瘤及其变异体的细胞遗传学和分子生物学研究正在取得进展，这可能最终改变我们对其病理学、诊断以及潜在治疗的理解。
Uterine smooth muscle tumors are common and pose a significant public health problem for women of reproductive age. Although most uterine smooth muscle tumors are benign, pathologic diagnosis of the infrequent malignant leiomyosarcoma is important for clinical management and prediction of clinical outcome. Pathologic criteria for diagnosing malignancy in uterine smooth muscle tumors and studies of their validity are reviewed. Advances in the cytogenetic and molecular biologic study of uterine leiomyomas and their variants are being made which may ultimately change our understanding of their pathobiology, diagnosis, and potentially, their treatment.